Male reproductive health in cystic fibrosis

被引：29

作者：

Yoon, John C. ^{[1
]}

Casella, Julio Leey ^{[2
]}

Litvin, Marina ^{[3
]}

Dobs, Adrian S. ^{[4
]}

机构：

[1] Univ Calif Davis, Dept Internal Med, Sch Med, Div Endocrinol Diabet & Metab, Sacramento, CA 95817 USA

[2] Univ Florida, Dept Med, Sch Med, Div Endocrinol Diabet & Metab, Gainesville, FL USA

[3] Washington Univ, Sch Med, Dept Internal Med, Div Endocrinol Metab & Lipid Res, St Louis, MO 63110 USA

[4] Johns Hopkins Sch Med, Div Endocrinol & Metab, Baltimore, MD USA

来源：

JOURNAL OF CYSTIC FIBROSIS | 2019年 / 18卷

关键词：

Cystic fibrosis; Infertility; Hypogonadism; Obstructive azoospermia; Testosterone deficiency;

D O I：

10.1016/j.jcf.2019.08.007

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The impact of cystic fibrosis (CF) on male reproductive health is profound. The vast majority of men with CF are infertile due to obstructive azoospermia. Multiple factors associated with CF contribute to an increased prevalence of testosterone deficiency, which adversely affects muscle mass, bone density, and quality of life. This article reviews the pathophysiology, diagnosis, and management of infertility and testosterone deficiency that occur in men with CF. With improving survival of CF patients, these topics are becoming more significant in their clinical care. (C) 2019 The Authors. Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society.

引用

页码：S105 / S110

页数：6

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