Rabbit and monkey visual cortex:: more than a year of recording with up to 64 microelectrodes

被引：36

作者：

Porada, I ^{[1
]}

Bondar, I ^{[1
]}

Spatz, WB ^{[1
]}

Krüger, J ^{[1
]}

机构：

[1] Univ Freiburg, AG Hirnforsch, Inst Biophys, D-79104 Freiburg, Germany

来源：

JOURNAL OF NEUROSCIENCE METHODS | 2000年 / 95卷 / 01期

关键词：

monkey; rabbit; cortex; multielectrode; microelectrode; chronic implant;

D O I：

10.1016/S0165-0270(99)00139-9

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

In the visual cortex of rabbits and a marmoset monkey, 32 and 64 microwires, respectively, were chronically implanted by an indirect insertion method so that the cortex was penetrated from the white matter. For more than 1 year recordings of action potentials of good quality were obtained at most electrodes. Recording stability was judged by spike shape, spike train autocorrelograms, and spike rates: within recording sessions, stability was essentially perfect. Periods in which the signals of several electrodes were stable could last for several days. A method of in vivo reconstruction of the electrode locations by micro-X-rays and subsequent stereophotogrammetry is presented. The aspect of animal welfare is considered. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：13 / 28

页数：16