Graphene based scaffolds effects on stem cells commitment

被引：96

作者：

Bressan, Eriberto ^{[1
]}

Ferroni, Letizia ^{[2
]}

Gardin, Chiara ^{[2
]}

Sbricoli, Luca ^{[1
]}

Gobbato, Luca ^{[1
]}

Ludovichetti, Francesco Saverio ^{[1
]}

Tocco, Ilaria ^{[3
]}

Carraro, Amedeo ^{[4
]}

Piattelli, Adriano ^{[5
]}

Zavan, Barbara ^{[2
]}

机构：

[1] Univ Padua, Dept Neurosci, I-35131 Padua, Italy

[2] Univ Padua, Dept Biomed Sci, I-35131 Padua, Italy

[3] Univ Hosp Padova, Inst Plast Surg, I-35131 Padua, Italy

[4] Univ Hosp Verona, Gen Surg & Liver Transplant Unit, Dept Gen Surg & Odontoiatr, I-37126 Verona, Italy

[5] Univ G dAnnunzio, Dept Med Oral & Biotechnol Sci, I-66100 Chieti, Italy

来源：

JOURNAL OF TRANSLATIONAL MEDICINE | 2014年 / 12卷

关键词：

Graphene; Tissue engineering; Stem cells; Oosteogenic differentiation; Neuronal differentiation; Adipogenic differentiation; OSTEOGENIC DIFFERENTIATION; CARBON NANOTUBES; CULTURE;

D O I：

10.1186/s12967-014-0296-9

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Graphene is a flat monolayer of carbon atoms, arranged in a two-dimensional hexagonal structure, with extraordinary electrical, thermal, and physical properties. Moreover, the molecular structure of graphene can be chemically modified with molecules of interest to promote the development of high-performance devices. Although carbon derivatives have been extensively employed in industry and electronics, their use in regenerative medicine is still in an early phase. Study prove that graphene is highly biocompatible, has low toxicity and a large dosage loading capacity. This review describes the ability of graphene and its related materials to induce stem cells differentiation into osteogenic, neuronal, and adipogenic lineages.

引用

页数：15

共 51 条

[1] Flash photo stimulation of human neural stem cells on graphene/TiO2 heterojunction for differentiation into neurons [J].