Therapeutic potential of vitamin D-binding protein

被引：162
|
作者：
Gomme, PT [1 ]
Bertolini, J [1 ]
机构：
[1] CSL Ltd, Res & Dev, Bioplasma Div, Broadmeadows, Vic 3047, Australia
来源：
TRENDS IN BIOTECHNOLOGY | 2004年 / 22卷 / 07期
关键词：
D O I：
10.1016/j.tibtech.2004.05.001
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Vitamin D-binding protein (DBP) is a multi-functional plasma protein with many important functions. These include transport of vitamin D metabolites, control of bone development, binding of fatty acids, sequestration of actin and a range of less-defined roles in modulating immune and inflammatory responses. Exploitation of the unique properties of DBP could enable the development of important therapeutic agents for the treatment of a variety of diseases.
引用
收藏
页码：340 / 345
页数：6
相关论文
共 50 条
  • [1] Vitamin D-Binding Protein
    Vilaca, Tatiane
    Lazaretti-Castro, Marise
    VITAMIN D IN CLINICAL MEDICINE, 2018, 50 : 31 - 41
  • [2] Vitamin D-Binding Protein and Vitamin D in Blacks and Whites
    Chen, Yu
    NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (09): : 878 - 879
  • [3] Vitamin D and Vitamin D-Binding Protein in Health and Disease
    Delrue, Charlotte
    Speeckaert, Marijn M.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (05)
  • [4] Molecular recognition in vitamin D-binding protein
    Ray, R
    PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, 1996, 212 (04): : 305 - 312
  • [5] THE POLYMORPHISM AND THE EVOLUTION OF VITAMIN D-BINDING PROTEIN
    CONSTANS, J
    JAPANESE JOURNAL OF HUMAN GENETICS, 1984, 29 (02): : 173 - 174
  • [6] Vitamin D-binding protein and free vitamin D concentrations in acromegaly
    Alev Eroglu Altinova
    Cigdem Ozkan
    Mujde Akturk
    Ozlem Gulbahar
    Muhittin Yalcin
    Nuri Cakir
    Fusun Balos Toruner
    Endocrine, 2016, 52 : 374 - 379
  • [7] Vitamin D-Binding Protein and Vitamin D in Blacks and Whites REPLY
    Powe, Camille E.
    Karumanchi, S. Ananth
    Thadhani, Ravi
    NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (09): : 880 - 881
  • [8] Nonhypercalcemic vitamin D analogs: Interactions with the vitamin D-binding protein
    Bouillon, R
    Verstuyf, A
    Zhao, J
    Tan, BK
    VanBaelen, H
    HORMONE RESEARCH, 1996, 45 (3-5) : 117 - 121
  • [9] Vitamin D-binding protein and free vitamin D concentrations in acromegaly
    Altinova, Alev Eroglu
    Ozkan, Cigdem
    Akturk, Mujde
    Gulbahar, Ozlem
    Yalcin, Muhittin
    Cakir, Nuri
    Toruner, Fusun Balos
    ENDOCRINE, 2016, 52 (02) : 374 - 379
  • [10] The multifunctional properties and characteristics of vitamin D-binding protein
    White, P
    Cooke, N
    TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2000, 11 (08): : 320 - 327
12345