SPR for molecular interaction analysis: a review of emerging application areas

被引：337
作者：
Karlsson, R [1 ]
机构：
[1] Biacore AB, SE-75450 Uppsala, Sweden
来源：
JOURNAL OF MOLECULAR RECOGNITION | 2004年 / 17卷 / 03期
关键词：
surface plasmon resonance; biacore; food analysis; proteornies; immunogenicity; drug discovery; ADME;
D O I：
10.1002/jmr.660
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
PubMed searches identified four emerging application areas for surface plasmon resonance systems. Food analysis, proteomics, immunogenicity and drug discovery. These application areas are reviewed. In connection with the review of drug discovery applications a case study is presented. This study demonstrates the value of combining results from drug-target and ADME predictive assays for compound selection. Copyright (C) 2004 John Wiley Sons, Ltd.
引用
收藏
页码：151 / 161
页数：11
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