Cerebral white matter hyperintensities are not increased in patients with primary Sjogren's syndrome

被引：17

作者：

Harboe, E. ^{[1
]}

Beyer, M. K. ^{[2
]}

Greve, O. J. ^{[2
]}

Goransson, L. G. ^{[1
,3
]}

Tjensvoll, A. B. ^{[4
]}

Kvaloy, J. T. ^{[5
,6
]}

Omdal, R. ^{[1
,3
]}

机构：

[1] Stavanger Univ Hosp, Dept Internal Med, Clin Immunol Unit, N-4068 Stavanger, Norway

[2] Stavanger Univ Hosp, Dept Radiol, N-4068 Stavanger, Norway

[3] Univ Bergen, Inst Internal Med, Bergen, Norway

[4] Stavanger Univ Hosp, Dept Neurol, N-4068 Stavanger, Norway

[5] Univ Stavanger, Dept Math & Nat Sci, Stavanger, Norway

[6] Stavanger Univ Hosp, Div Res & Human Resources, N-4068 Stavanger, Norway

来源：

EUROPEAN JOURNAL OF NEUROLOGY | 2009年 / 16卷 / 05期

关键词：

cerebral MRI; controlled study; Sjogren's syndrome; white matter; SYSTEMIC-LUPUS-ERYTHEMATOSUS; MULTIPLE-SCLEROSIS; LESIONS; DISEASE; MRI; CRITERIA; SCALE;

D O I：

10.1111/j.1468-1331.2009.02537.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

It is frequently thought that cerebral white matter hyperintensities (WMHs) on T-2 weighted MRI scans are increased in patients with autoimmune diseases. An increased frequency of WHMs has been described in primary Sjogren's syndrome (PSS), but no controlled studies exist. The aim of this study was therefore to compare WMHs in PSS patients and healthy subjects applying the new European-American criteria for PSS. Cross-sectional controlled study of 68 unselected PSS patients and 68 healthy subjects was carried out. WMHs were rated using Scheltens method. There were no differences in total or any regional WMH scores between PSS patients and healthy subjects. Patients with PSS do not have increased WMH load or distribution when compared with healthy subjects.

引用

页码：576 / 581

页数：6

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