A PEGylated-rhodamine based sensor for "turn-on" fluorimetric and colorimetric detection of Hg2+ ions in aqueous media

被引：23

作者：

Hazra, Subhenjit ^{[1
]}

Balaji, Shruti ^{[2
]}

Banerjee, Mainak ^{[1
]}

Ganguly, Anasuya ^{[2
]}

Ghosh, Narendra Nath ^{[1
]}

Chatterjee, Amrita ^{[1
]}

机构：

[1] BITS, Dept Chem, Zuarinagar, Goa, India

[2] BITS, Dept Biol Sci, Zuarinagar, Goa, India

来源：

ANALYTICAL METHODS | 2014年 / 6卷 / 11期

关键词：

INORGANIC MERCURY; FLUORESCENCE ENHANCEMENT; SENSING MERCURY; FISH; HG(II); WATER; TOXICOLOGY; TRANSPORT; CADMIUM; DESIGN;

D O I：

10.1039/c4ay00265b

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A water soluble turn-on fluorescent probe for the detection of mercury ions in water is developed by appending a water-compatible PEG-unit onto a rhodamine derivative. The probe, Rh1 responds to Hg2+ ions with an intense pink colour and orange fluorescence due to Hg2+ ion-induced opening of the spirolactam ring with high selectivity and sensitivity. The Job's plot reveals that a 1 : 1 stoichiometry was most favourable for the binding mode of Hg2+ and the probe. Preliminary studies revealed that the probe molecule is fairly non-toxic and can successfully penetrate the cell surface of HeLa cells and interact with intercellular Hg2+ ions, indicating its usefulness for monitoring Hg2+ ions in biological samples as well. The probe is highly efficient, cost-effective and shows a low detection limit of 0.14 ppm.

引用

页码：3784 / 3790

页数：7

共 46 条

[1] A near IR di-styryl BODIPY-based ratiometric fluorescent chemosensor for Hg(II) [J].