The hypothalamic-pituitary-adrenal axis in anorexia nervosa

被引：106
作者：
Licinio, J
Wong, ML
Gold, PW
机构：
来源：
PSYCHIATRY RESEARCH | 1996年 / 62卷 / 01期
关键词：
cortisol; adrenocorticotropic hormone; corticotropin-releasing hormone; circadian rhythms; depression;
D O I：
10.1016/0165-1781(96)02991-5
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Studies examining the function of the hypothalamic-pituitary-adrenal (HPA) axis in anorexia nervosa are reviewed. A principal finding is that of hypercortisolism, associated with increased central corticotropin-releasing hormone levels and normal circulating levels of adrenocorticotropic hormone. Similarities between neuroendocrine findings in anorexia nervosa and in affective disorder are reviewed. The contribution of circadian rhythm disturbances and malnutrition to observed HPA axis abnormalities in anorexia nervosa is also considered. Directions for future research are discussed.
引用
收藏
页码：75 / 83
页数：9
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