Escherichia coli O157:H7 causes more-severe systemic disease in suckling piglets than in colostrum-deprived neonatal piglets

被引：33
作者：
Dean-Nystrom, EA
Pohlenz, JFL
Moon, HW
O'Brien, AD
机构：
[1] ARS, Enter Dis & Food Safety Res Unit, Natl Anim Dis Ctr, USDA, Ames, IA 50010 USA
[2] Univ Hannover, Sch Vet Med, Inst Pathol, Hannover, Germany
[3] Iowa State Univ, Dept Vet Pathol, Ames, IA 50011 USA
[4] Uniformed Serv Univ Hlth Sci, F Edward Hebert Sch Med, Dept Microbiol & Immunol, Bethesda, MD 20814 USA
来源：
INFECTION AND IMMUNITY | 2000年 / 68卷 / 04期
关键词：
D O I：
10.1128/IAI.68.4.2356-2358.2000
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Our objective was to determine if suckling neonatal piglets are susceptible to enterohemorrhagic Escherichia coli (EHEC) O157:H7 disease. Surprisingly, EHEC O157:H7 caused more-rapid and more-severe neurological disease in suckling neonates than in those fed an artificial diet. Shiga toxin-negative O157:H7 did not cause neurological disease but colonized and caused attaching-and-effacing intestinal lesions.
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页码：2356 / 2358
页数：3
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