Celiac disease: a clinical review

被引：27
作者：
Al-Bawardy, Badr [1 ]
Codipilly, D. Chamil [2 ]
Rubio-Tapia, Alberto [1 ]
Bruining, David H. [1 ]
Hansel, Stephanie L. [1 ]
Murray, Joseph A. [1 ]
机构：
[1] Mayo Clin, Div Gastroenterol & Hepatol, 200 First St,SW, Rochester, MN 55905 USA
[2] Mayo Clin, Dept Internal Med, Rochester, MN USA
来源：
ABDOMINAL RADIOLOGY | 2017年 / 42卷 / 02期
基金：
美国国家卫生研究院;
关键词：
Celiac disease; Enteropathy; Sprue; Gluten free; Refractory; imaging; GLUTEN-FREE DIET; T-CELL LYMPHOMA; NUTRITION EXAMINATION SURVEYS; PRIMARY BILIARY-CIRRHOSIS; INCREASED RISK; MICROSCOPIC COLITIS; THYROID-DISEASE; NATIONAL-HEALTH; HIGH PREVALENCE; UNITED-STATES;
D O I：
10.1007/s00261-016-1034-y
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Celiac disease (CD) is an immune-mediated inflammatory enteropathy triggered by gluten exposure in genetically susceptible individuals. It has a high prevalence approaching 1% of the US population. A high index of suspicion is warranted to diagnose CD as frequently patients present with extraintestinal or atypical manifestations. CD is diagnosed by a combination of serum serologies and duodenal biopsies. The majority of patients will respond to a lifelong gluten-free diet which is the cornerstone of therapy. Complications such as refractory CD, ulcerative jejunoileitis, enteropathy associated T-cell lymphoma and small bowel adenocarcinoma occur in a minority of patients.
引用
收藏
页码：351 / 360
页数：10
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