Long-term potentiation in the in vitro perirhinal cortex displays associative properties

被引：43

作者：

Bilkey, DK ^{[1
]}

机构：

[1] UNIV OTAGO,CTR NEUROSCI,DUNEDIN,NEW ZEALAND

来源：

BRAIN RESEARCH | 1996年 / 733卷 / 02期

关键词：

long-term potentiation; perirhinal cortex; NMDA; associative; memory;

D O I：

10.1016/0006-8993(96)00789-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Brief high frequency tetanization trains reliably induced input-specific long-term potentiation (LTP) in slices of rat perirhinal cortex maintained in vitro. Furthermore, associative interactions between inputs were observed following simultaneous tetanization of separate inputs. This associativity may be mediated via NMDA receptors as LTP was blocked in the presence of APV. These results suggest that LTP may underlie the participation of perirhinal cortex in memory processes.

引用

页码：297 / 300

页数：4

共 15 条

[1] POSTSYNAPTIC HEBBIAN AND NON-HEBBIAN LONG-TERM POTENTIATION OF SYNAPTIC EFFICACY IN THE ENTORHINAL CORTEX IN SLICES AND IN THE ISOLATED ADULT GUINEA-PIG BRAIN [J].