Patient preparation for cardiac fluorine-18 fluorodeoxyglucose positron emission tomography imaging of inflammation

被引:166
作者
Osborne, Michael T. [1 ,2 ,3 ,4 ]
Hulten, Edward A. [5 ,6 ]
Murthy, Venkatesh L. [7 ,8 ,9 ]
Skali, Hicham [2 ,3 ,4 ]
Taqueti, Viviany R. [2 ,3 ,4 ]
Dorbala, Sharmila [2 ,3 ,4 ]
DiCarli, Marcelo F. [2 ,3 ,4 ]
Blankstein, Ron [2 ,3 ,4 ]
机构
[1] Massachusetts Gen Hosp, Dept Med, Div Cardiol, Boston, MA 02114 USA
[2] Harvard Med Sch, Boston, MA 02115 USA
[3] Brigham & Womens Hosp, Dept Med, Noninvas Cardiovasc Imaging Program, 75 Francis St, Boston, MA 02115 USA
[4] Brigham & Womens Hosp, Dept Radiol, 75 Francis St, Boston, MA 02115 USA
[5] Walter Reed Natl Mil Med Ctr, Div Med, Serv Cardiol, Bethesda, MD USA
[6] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA
[7] Univ Michigan, Dept Med, Div Cardiovasc Med, Ann Arbor, MI 48109 USA
[8] Univ Michigan, Dept Radiol, Div Nucl Med, Ann Arbor, MI 48109 USA
[9] Univ Michigan, Dept Radiol, Div Cardiothorac Imaging, Ann Arbor, MI 48109 USA
关键词
PET imaging; fluorodeoxyglucose (FDG); metabolism; inflammation; LOW-CARBOHYDRATE-DIET; HIGH-FAT; FDG UPTAKE; SUPPRESSION; SARCOIDOSIS; GLUCOSE; PET/CT; HEART; RESTRICTION; HEPARIN;
D O I
10.1007/s12350-016-0502-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Although the number of clinical applications for fluorine-18 fluorodeoxyglucose (F-18-FDG) cardiac positron emission tomography (PET) has continued to grow, there remains a lack of consensus regarding the ideal method of suppressing normal myocardial glucose utilization for image optimization. This review describes various patient preparation protocols that have been used as well as the success rates achieved in different studies. Collectively, the available literature supports using a high-fat, no-carbohydrate diet for at least two meals with a fast of 4-12 hours prior to F-18-FDG PET imaging and suggests that isolated fasting for less than 12 hours and supplementation with food or drink just prior to imaging should be avoided. Each institution should adopt a protocol and continuously monitor its effectiveness with a goal to achieve adequate myocardial suppression in greater than 80% of patients.
引用
收藏
页码:86 / 99
页数:14
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