Visible Light Promoted Benzylic CSp3-H Bond Activation and Functionalization

In recent years, visible-light-promoted photoredox catalytic activation of organic molecules has been flourishing vigorously. This kind of methodology usually takes advantage of transition-metal complexes and organic dyes as photosensitizers, which can directly react with organic substrates through a single-electron-transfer (SET) progress under visible light irradiation. It's operable to construct C-X (X= C, N, 0 ...) bond via the radical or radical ion generated during the SET process. On the basis of different key intermediates, this highlight gives a brief summary on the recent development of visible light promoted benzylic C-sp3-H activation and functionalization.