Risk factor analysis of postoperative acute respiratory distress syndrome in valvular heart surgery

被引：24

作者：

Chen, Shao-Wei ^{[1
,2
]}

Chang, Chih-Hsiang ^{[2
,3
]}

Chu, Pao-Hsien ^{[4
]}

Chen, Tien-Hsing ^{[4
]}

Wu, Victor Chien-Chia ^{[4
]}

Huang, Yao-Kuang ^{[1
]}

Liao, Chien-Hung ^{[5
]}

Wang, Shang-Yu ^{[2
,5
]}

Lin, Pyng-Jing ^{[1
]}

Tsai, Feng-Chun ^{[1
]}

机构：

[1] Chang Gung Mem Hosp, Linkou Med Ctr, Dept Cardiothorac & Vasc Surg, Taoyuan 33305, Taiwan

[2] Chang Gung Univ, Coll Med, Grad Inst Clin Med Sci, Taoyuan, Taiwan

[3] Chang Gung Mem Hosp, Linkou Med Ctr, Dept Nephrol, Kidney Res Ctr, Taoyuan 33305, Taiwan

[4] Chang Gung Mem Hosp, Linkou Med Ctr, Dept Cardiol, Taoyuan 33305, Taiwan

[5] Chang Gung Mem Hosp, Linkou Med Ctr, Dept Traumatol & Emergency Surg, Taoyuan 33305, Taiwan

来源：

JOURNAL OF CRITICAL CARE | 2016年 / 31卷 / 01期

关键词：

Valvular heart surgery; Acute respiratory distress syndrome; TRICUSPID-VALVE SURGERY; ACUTE LUNG INJURY; CARDIAC-SURGERY; MULTICENTER COHORT; BERLIN DEFINITION; PREDICTION; ARDS;

D O I：

10.1016/j.jcrc.2015.11.002

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Purpose: The aim of this study is to investigate the incidence, severity, and outcome of postoperative acute respiratory distress syndrome (ARDS), according to the Berlin definition, in isolated valvular heart surgery. The preoperative and perioperative predisposing factors of this complication were also identified. Methods: A retrospective chart review was conducted on 457 patients who underwent isolated valvular heart surgery between January 2010 and December 2012. Clinical characteristics and outcomes were collected. The primary outcome was postoperative ARDS, according to the 2012 Berlin definition for ARDS. Results: A total of 37 patients (8.1%) developed postoperative ARDS, with a mortality rate of 29.7%. The multivariate analysis identified that age (odds ratios [ORs], 1.067, P <= .001), liver cirrhosis (OR, 7.159; P = .001), massive blood transfusion (OR, 2.980; P = .005), and tricuspid valve replacement (OR, 5.197; P = .012) were independent risk factors of postoperative ARDS. Furthermore, we have determined that the increased severity stages of ARDS were associated with decreased postoperative survival. Conclusions: In conclusion, postoperative ARDS, according to Berlin definition, in valvular surgery, was associated with high in-hospital mortality. The severity of ARDS was associated with patient midterm mortality. In multivariate analysis, age, liver cirrhosis, massive blood transfusion, and tricuspid valve replacement were identified as independent risk factors of ARDS. (C) 2015 Elsevier Inc. All rights reserved.

引用

页码：139 / 143

页数：5

共 21 条

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