Optimal Control of HIV/AIDS in the Workplace in the Presence of Careless Individuals

被引:26
作者
Seidu, Baba [1 ]
Makinde, Oluwole D. [2 ]
机构
[1] Univ Dev, Fac Math Sci, Dept Appl Math, Navrongo, Ghana
[2] Univ Stellenbosch, Fac Mil Sci, ZA-7395 Saldanha, South Africa
关键词
HIV; IMPACT; DISEASE; MODELS; AIDS;
D O I
10.1155/2014/831506
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A nonlinear dynamical system is proposed and qualitatively analyzed to study the dynamics of HIV/AIDS in the workplace. The disease-free equilibrium point of the model is shown to be locally asymptotically stable if the basic reproductive number, R-0, is less than unity and the model is shown to exhibit a unique endemic equilibrium when the basic reproductive number is greater than unity. It is shown that, in the absence of recruitment of infectives, the disease is eradicated when R-0 < 1, whiles the disease is shown to persist in the presence of recruitment of infected persons. The basic model is extended to include control efforts aimed at reducing infection, irresponsibility, and nonproductivity at the workplace. This leads to an optimal control problem which is qualitatively analyzed using Pontryagin's Maximum Principle (PMP). Numerical simulation of the resulting optimal control problem is carried out to gain quantitative insights into the implications of the model. The simulation reveals that a multifaceted approach to the fight against the disease is more effective than single control strategies.
引用
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页数:19
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