Factors associated with extubation time in coronary artery bypass grafting patients

被引:9
作者
Rezaianzadeh, Abbas [1 ]
Maghsoudi, Behzad [2 ]
Tabatabaee, Hamidreza [3 ]
Keshavarzi, Sareh [3 ]
Bagheri, Zahra [4 ]
Sajedianfard, Javad [5 ]
Gerami, Hamid [2 ]
Rasouli, Javad [3 ]
机构
[1] Shiraz Univ Med Sci, Dept Epidemiol, Sch Hlth, Colorectal Res Ctr, Shiraz, Iran
[2] Shiraz Univ Med Sci, Shiraz Med Sch, Dept Anesthesia, Shiraz, Iran
[3] Shiraz Univ Med Sci, Dept Epidemiol, Sch Hlth, Shiraz Fars, Iran
[4] Shiraz Univ Med Sci, Shiraz Med Sch, Dept Biostat, Shiraz, Iran
[5] Shiraz Univ, Sch Vet Med, Dept Physiol, Shiraz, Iran
关键词
Coronary Artery Bypass; Risk factors; Extubation; PROLONGED MECHANICAL VENTILATION; CARE-UNIT STAY; PATH-ANALYSIS; RISK-FACTORS; SURGERY; PREDICTORS; DURATION; OUTCOMES; DISEASE;
D O I
10.7717/peerj.1414
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background and Objectives. Cardiovascular diseases are the leading cause of death worldwide, with coronary artery disease being the most common. With increasing numbers of patients, Coronary Artery Bypass Grafting (CABG) has become the most common operation in the world. Respiratory disorder is one of the most prevalent complications of CABG. Thus, weaning off the mechanical ventilation and extubation are of great clinical importance for these patients. Some post-operative problems also relate to the tracheal tube and mechanical ventilation. Therefore, an increase in this leads to an increase in the number of complications, length of hospital stay, and treatment costs. Since a large number of factors affect the post-operative period, the present study aims to identify the predictors of extubation time in CABG patients using casualty network analysis. Method. This longitudinal study was conducted on 800 over 18 year old patients who had undergone CABG surgery in three treatment centers affiliated to Shiraz University of Medical Sciences. The patients' information, including pre-operative, peri-operative, and post-operative variables, was retrospectively extracted from their medical records. Then, the data was comprehensively analyzed through path analysis using MPLUS-7.1 software. Results. The mean of extubation time was 10.27+4.39 h. Moreover, extubation time was significantly affected by packed cells during the Cardiopulmonary Bypass (CPB), packed cells after CPB, inotrope use on arrival at ICU, mean arterial pressure 1st ICU, packed cells 1st ICU, platelets 1st ICU, Blood Urea Nitrogen 1st ICU, and hematocrit 1st ICU. Conclusion. Considering all of the factors under investigation, some peri-operative and post-operative factors had significant effects. Therefore, considering the post-operative factors is important for designing a treatment plan and evaluating patients' prognosis.
引用
收藏
页数:11
相关论文
共 29 条
[1]  
[Anonymous], 2000, MODELS REASONING INF
[2]   Off-pump coronary artery bypass graft surgery: the incidence of postoperative atrial fibrillation [J].
Archbold, RA ;
Curzen, NP .
HEART, 2003, 89 (10) :1134-1137
[3]  
Azarfarin Rasoul, 2014, Res Cardiovasc Med, V3, pe20159, DOI 10.5812/cardiovascmed.20159
[4]   Factors associated with prolonged mechanical ventilation following coronary artery bypass surgery [J].
Branca, P ;
McGaw, P ;
Light, RW .
CHEST, 2001, 119 (02) :537-546
[5]  
Christian K, 2011, AM SURGEON, V77, P942
[6]   Does the duration of surgery affect outcomes in patients undergoing coronary artery bypass grafting? [J].
Chu, Danny ;
Bakaeen, Faisal G. ;
Wang, Xing Li ;
LeMaire, Scott A. ;
Coselli, Joseph S. ;
Huh, Joseph .
AMERICAN JOURNAL OF SURGERY, 2008, 196 (05) :652-656
[7]   Morbid results of prolonged intubation after coronary artery bypass surgery [J].
Cohen, AJ ;
Katz, MG ;
Frenkel, G ;
Medalion, B ;
Geva, D ;
Schachner, A .
CHEST, 2000, 118 (06) :1724-1731
[8]   Perioperative predictors of ICU and hospital costs in coronary artery bypass graft surgery [J].
Doering, LV ;
Esmailian, F ;
Laks, H .
CHEST, 2000, 118 (03) :736-743
[9]   Immediate Extubation After Off-Pump Coronary Artery Bypass Graft Surgery in 1,196 Consecutive Patients: Feasibility, Safety and Predictors of When Not To Attempt It [J].
Dorsa, Alberto G. ;
Rossi, Adriana I. ;
Thierer, Jorge ;
Lupianez, Bernardo ;
Vrancic, Juan M. ;
Vaccarino, Guillermo N. ;
Piccinini, Fernando ;
Raich, Hernan ;
Bonazzi, Solange V. ;
Benzadon, Mariano ;
Navia, Daniel O. .
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 2011, 25 (03) :431-436
[10]   Perioperative risk factors for prolonged mechanical ventilation and tracheostomy in women undergoing coronary artery bypass graft with cardiopulmonary bypass [J].
Faritous, Zahra S. ;
Aghdaie, Nahid ;
Yazdanian, Forouzan ;
Azarfarin, Rasoul ;
Dabbagh, Ali .
SAUDI JOURNAL OF ANAESTHESIA, 2011, 5 (02) :167-169