Comparison Between Intravenous and Intra-articular Regimens of Tranexamic Acid in Reducing Blood Loss During Total Knee Arthroplasty

被引：92

作者：

Soni, Ashwani ^{[1
]}

Saini, Raghav ^{[2
]}

Gulati, Anmol ^{[2
]}

Paul, Rajesh ^{[1
]}

Bhatty, Shiraj ^{[1
]}

Rajoli, Sreekanth Reddy ^{[3
]}

机构：

[1] GGS Med Coll & Hosp, Dept Orthopaed, Faridkot, India

[2] Shivam Multispecialty Hosp, Dept Orthopaed, Hoshiarpur, India

[3] Postgrad Inst Med Educ & Res, Dept Orthopaed, Chandigarh 160012, India

来源：

JOURNAL OF ARTHROPLASTY | 2014年 / 29卷 / 08期

关键词：

tranexamic acid; total knee arthroplasty; blood loss; antifibrinolytic; PNEUMATIC TOURNIQUET; REPLACEMENT; SURGERY; FIBRINOLYSIS; CONSERVATION; METAANALYSIS; EFFICACY; RELEASE; TRIAL;

D O I：

10.1016/j.arth.2014.03.039

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Tranexamic acid is an antifibrinolytic drug used widely to prevent bleeding. Its use in reducing bleeding during total knee arthroplasty surgery is well proven but there is no final consensus regarding the regimen. The purpose of our study was to compare the effectiveness of intravenous and intra-articular regimen of tranexamic acid during the total knee arthroplasty surgery. A total of 40 patients were received three doses of intravenous tranexamic acid during total knee arthroplasty surgery. Intra-articular tranexamic acid was used in 40 patients during the surgery. We concluded that intra-articular tranexamic acid is equally effective as three dose intravenous regimen in reducing blood loss during total knee arthroplasty surgery. (C) 2014 Elsevier Inc. All rights reserved.

引用

页码：1525 / 1527

页数：3

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