Hydroalkylation of Alkenes Using Alkyl Iodides and Hantzsch Ester under Palladium/Light System

被引：31
作者：
Sumino, Shuhei [1 ]
Ryu, Ilhyong [1 ]
机构：
[1] Osaka Prefecture Univ, Grad Sch Sci, Dept Chem, Sakai, Osaka 5998531, Japan
来源：
ORGANIC LETTERS | 2016年 / 18卷 / 01期
基金：
日本学术振兴会;
关键词：
RADICAL CONJUGATE ADDITIONS; ELECTRON-DEFICIENT ALKENES; UNACTIVATED ALKYL; ARYLBORONIC ACIDS; COUPLING REACTION; VISIBLE-LIGHT; HECK REACTION; HALIDES; CARBONYLATION; DERIVATIVES;
D O I：
10.1021/acs.orglett.5b03238
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The hydroalkylation of alkenes using alkyl iodides with Hantzsch ester as a hydrogen source occurred smoothly under a Pd/light system, in a novel, tin-free Giese reaction. A chemoselective reaction at C(sp(3))-I in the presence of a C(sp(2))-X (X = Br or I) bond was attained, which allowed for the stepwise functionalization of two types of C-X bonds in a one-pot procedure.
引用
收藏
页码：52 / 55
页数：4
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