Temporal trends in cardiac arrest incidence and outcome in Finnish intensive care units from 2003 to 2013

被引:21
作者
Efendijev, I. [1 ]
Raj, R. [2 ]
Reinikainen, M. [3 ]
Hoppu, S. [4 ]
Skrifvars, M. B. [1 ]
机构
[1] Univ Helsinki, Cent Hosp, Dept Anaesthesia & Intens Care Med, Helsinki, Finland
[2] Univ Helsinki, Cent Hosp, Dept Neurosurg, Helsinki, Finland
[3] North Karelia Cent Hosp, Dept Intens Care, Joensuu, Finland
[4] Tampere Univ Hosp, Dept Intens Care, Tampere, Finland
关键词
Cardiopulmonary arrest; Incidence; Outcome; Hospital mortality; Intensive care; EUROPEAN RESUSCITATION COUNCIL; CARDIOPULMONARY-RESUSCITATION; APACHE-III; SURVIVAL; GUIDELINES; SCORE; ASSOCIATION; PREDICTION; MORTALITY; STATEMENT;
D O I
10.1007/s00134-014-3509-z
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
To estimate temporal trends in incidence and hospital mortality after cardiac arrest in Finnish intensive care units. Using a large nationwide intensive care unit (ICU) database we identified patients suffering from cardiac arrest following ICU admission (ICU-CA) during the study period (2003-2013). ICU-CA was defined as need for cardiopulmonary resuscitation and/or defibrillation (non-arrest cardioversions were excluded) according to the Therapeutic Intervention Scoring System-76. Patients admitted with an admission diagnosis of cardiac arrest were excluded. We determined crude incidence and risk-adjusted hospital mortality (based on a customized severity of illness model) for all ICU-CA patients, and for predefined admission diagnosis subgroups. Temporal trends for the observed period were calculated for crude incidence and risk-adjusted hospital mortality. Crude incidence for all ICU-CA patients was 29/1,000 ICU admissions, with the highest incidence 118/1,000 in the non-operative cardiovascular subgroup. Overall hospital mortality for ICU-CA patients was 55.5 % [95 % confidence interval (CI) 54-57 %]. Hospital mortality was 53.1 % (95 % CI 50.4-55.8 %) for non-operative cardiovascular ICU-CA patients, 32.9 % (95 % CI 26.9-38.9 %) for post cardiac surgery ICU-CA patients, and 56.3 % (95 % CI 51.2-61.3 %) for neurological/neurosurgical ICU-CA patients. There was a significant reduction in the overall ICU-CA incidence and in the risk-adjusted hospital mortality of ICU-CA and non-cardiac arrest cases (non-CA) over the observed study period (p < 0.001). Our data suggest that the incidence of ICU-CA has decreased in Finnish ICUs between 2003 and 2013. Similar reduction in hospital mortality over time was observed for both ICU-CA and non-CA populations.
引用
收藏
页码:1853 / 1861
页数:9
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