The MARK-AGE phenotypic database: Structure and strategy

被引：24

作者：

Moreno-Villanueva, Maria ^{[1
]}

Koetter, Tobias ^{[2
]}

Sindlinger, Thilo ^{[1
]}

Baur, Jennifer ^{[1
]}

Oehlke, Sebastian ^{[1
]}

Buerkle, Alexander ^{[1
]}

Berthold, Michael R. ^{[2
]}

机构：

[1] Univ Konstanz, Dept Biol, Mol Toxicol Grp, D-78457 Constance, Germany

[2] Univ Konstanz, Chair Bioinformat & Informat Min, D-78457 Constance, Germany

来源：

MECHANISMS OF AGEING AND DEVELOPMENT | 2015年 / 151卷

关键词：

Database; Data management;

D O I：

10.1016/j.mad.2015.03.005

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In the context of the MARK-AGE study, anthropometric, clinical and social data as well as samples of venous blood, buccal mucosal cells and urine were systematically collected from 3337 volunteers. Information from about 500 standardised questions and about 500 analysed biomarkers needed to be documented per individual. On the one hand handling with such a vast amount of data necessitates the use of appropriate informatics tools and the establishment of a database. On the other hand personal information on subjects obtained as a result of such studies has, of course, to be kept confidential, and therefore the investigators must ensure that the subjects' anonymity will be maintained. Such secrecy obligation implies a well-designed and secure system for data storage. In order to fulfil the demands of the MARK-AGE study we established a phenotypic database for storing information on the study subjects by using a doubly coded system. (C) 2015 Published by Elsevier Ireland Ltd.

引用

页码：26 / 30

页数：5