Gastric cancer patients at high-risk of having synchronous cancer

被引：73
作者：
Lee, Jun Ho [1 ]
Bae, Ja Seong [1 ]
Ryu, Keun Won [1 ]
Lee, Jong Seok [1 ]
Park, Sook Ryun [1 ]
Kim, Chan Gyoo [1 ]
Kook, Myoung Cheorl [1 ]
Choi, Il Ju [1 ]
Kim, Young Woo [1 ]
Park, Jae-Gahb [1 ]
Bae, Jae-Moon [1 ]
机构：
[1] Natl Canc Ctr, Res Inst & Hosp, Goyang 411769, Gyeonggi Do, South Korea
来源：
WORLD JOURNAL OF GASTROENTEROLOGY | 2006年 / 12卷 / 16期
关键词：
synchronous cancer; gastric cancer; colorectal cancer;
D O I：
10.3748/wjg.v12.i16.2588
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Aim: To identify patients with a high-risk of having a synchronous cancer among gastric cancer patients. Methods: We retrospectively analyzed the prospective gastric cancer database at the National Cancer Center, Korea from December 2000 to December 2004. The clinicopathological characteristics of patients with synchronous cancers and those of patients without synchronous cancers were compared. Multivariate analysis was performed to identify the risk factors for the presence of a synchronous cancer in gastric cancer patients. Results: 111 of 3291 gastric cancer patients (3.4%) registered in the database had a synchronous cancer. Among these 111 patients, 109 had a single synchronous cancer and 2 patients had two synchronous cancers. The most common form of synchronous cancer was colorectal cancer (42 patients, 37.2%) followed by lung cancer (21 patients, 18.6%). Multivariate analyses revealed that elderly patients with differentiated early gastric cancer have a higher probability of synchronous cancer. Conclusion: Synchronous cancers in gastric cancer patients are not infrequent. The physicians should try to find synchronous cancers in gastric cancer patients, especially in the elderly with a differentiated early gastric cancer. (C) 2006 The WJG Press. All rights reserved.
引用
收藏
页码：2588 / 2592
页数：5
相关论文
共 23 条
[1]  
Adachi Y, 2000, CANCER-AM CANCER SOC, V89, P1418
[2]   Improvement in preoperative staging of gastric adenocarcinoma with positron emission tomography [J].
Chen, J ;
Cheong, JH ;
Yun, MJ ;
Kim, J ;
Lim, JS ;
Hyung, WJ ;
Noh, SH .
CANCER, 2005, 103 (11) :2383-2390
[3]   MEDICAL PROGRESS - GASTRIC-CARCINOMA [J].
FUCHS, CS ;
MAYER, RJ .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (01) :32-41
[4]   Preoperative staging of gastric adenocarcinoma: Comparison of helical CT and endoscopic US [J].
Habermann, CR ;
Weiss, F ;
Riecken, R ;
Honarpisheh, H ;
Bohnacker, S ;
Staedtler, C ;
Dieckmann, C ;
Schoder, V ;
Adam, G .
RADIOLOGY, 2004, 230 (02) :465-471
[5]   Extended lymph node dissection for gastric cancer: Who may benefit? Final results of the randomized Dutch Gastric Cancer Group Trial [J].
Hartgrink, HH ;
van de Velde, CJH ;
Putter, H ;
Bonenkamp, JJ ;
Kranenbarg, EK ;
Songun, I ;
Welvaart, K ;
van Krieken, JHJM ;
Meijer, S ;
Plukker, JTM ;
van Elk, PJ ;
Obertop, H ;
Gouma, DJ ;
van Lanschot, JJB ;
Taat, CW ;
de Graaf, PW ;
von Meyenfeldt, MF ;
Tilanus, H ;
Sasako, M .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (11) :2069-2077
[6]   Multiple synchronous primaries of the gastrointestinal tract: A molecular case report [J].
Herring, JA ;
Shivangi, U ;
Hall, CC ;
Mihas, AA ;
Lynch, C ;
VijayMunshi, N ;
Hall, TJ .
CANCER LETTERS, 1996, 110 (1-2) :1-9
[7]   Features of second primary cancer in patients with gastric cancer [J].
Ikeda, Y ;
Saku, M ;
Kawanaka, H ;
Nonaka, M ;
Yoshida, K .
ONCOLOGY, 2003, 65 (02) :113-117
[8]  
KATO I, 1986, JPN J CLIN ONCOL, V16, P373
[9]   Preoperative evaluation of gastric cancer: value of spiral CT during gastric arteriography (CTGA) [J].
Kim, HS ;
Han, HY ;
Choi, JA ;
Park, CM ;
Cha, IH ;
Chung, KB ;
Mok, YJ .
ABDOMINAL IMAGING, 2001, 26 (02) :123-130
[10]   Gastric cancer surgery in cirrhotic patients: Result of gastrectomy with D2 lymph node dissection [J].
Lee, Jun Ho ;
Kim, Junuk ;
Cheong, Jae Ho ;
Hyung, Woo Jin ;
Choi, Seung Ho ;
Noh, Sung Hoon .
WORLD JOURNAL OF GASTROENTEROLOGY, 2005, 11 (30) :4623-4627
123