Oral Administration of the LSD1 Inhibitor OG-S1335 Increases Fetal Hemoglobin in Humanized Transgenic Sickle Cell Disease Mice and in Baboons

被引：0
|
作者：
Rivers, Angela
Vaitkus, Kestis
Jagadeeswaran, Ramasamy
Ibanez, Vinzon
Ruiz, Maria Armila
Ciceri, Filippo
Cavalcanti, Fernando
Molokie, Robert E.
Lavelle, Donald
机构：
来源：
BLOOD | 2017年 / 130卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
356
引用
收藏
页数：2
相关论文
共 3 条
  • [1] Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons
    Rivers, Angela
    Vaitkus, Kestis
    Jagadeeswaran, Ramasamy
    Ruiz, Maria Armila
    Ibanez, Vinzon
    Ciceri, Filippo
    Cavalcanti, Fernando
    Molokie, Robert E.
    Saunthararajah, Yogen
    Engel, James Douglas
    DeSimone, Joseph
    Lavelle, Donald
    EXPERIMENTAL HEMATOLOGY, 2018, 67 : 60 - 64
  • [2] The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice
    Cui, Shuaiying
    Lim, Kim-Chew
    Shi, Lihong
    Lee, Mary
    Jearawiriyapaisarn, Natee
    Myers, Greggory
    Campbell, Andrew
    Harro, David
    Iwase, Shigeki
    Trievel, Raymond C.
    Rivers, Angela
    DeSimone, Joseph
    Lavelle, Donald
    Saunthararajah, Yogen
    Engel, James Douglas
    BLOOD, 2015, 126 (03) : 386 - 396
  • [3] LSD1 Inhibition Induces Fetal Hemoglobin Expression and Provides a Novel Therapeutic Approach to Sickle Cell Disease
    Lee, Sang Hyun
    Soloviev, Maxim
    Zhang, Yan
    Roman, Valerie
    Yang, Gengjie
    Bowman, Kevin
    Burke, Krista
    Margulis, Alexander
    O'Connor, Sybil
    Yang, Yan-ou
    Wu, Liangxing
    Wynn, Richard
    Burn, Timothy
    Shuey, Dana
    Diamond, Sharon
    Yao, Wenqing
    Hollis, Gregory
    Yeleswaram, Swamy
    Roberts, Alan
    Huber, Reid
    Scherle, Peggy
    Ruggeri, Bruce
    BLOOD, 2016, 128 (22)
1