Labdane diterpenes from Marrubium thessalum

被引：22

作者：

Argyropoulou, Catherine ^{[1
]}

Karioti, Anastasia ^{[2
]}

Skaltsa, Helen ^{[1
]}

机构：

[1] Sch Pharm, Dept Pharmacognosy & Chem Nat Prod, GR-15771 Athens, Greece

[2] Univ Florence, Dept Pharmaceut Sci, I-50019 Florence, Italy

来源：

PHYTOCHEMISTRY | 2009年 / 70卷 / 05期

关键词：

Marrubium thessalum; Lamiaceae; Labdane diterpenes; 2D NMR; Marrubiin; Ladanein; VELUTINUM; VULGARE; FLAVONE; H-1;

D O I：

10.1016/j.phytochem.2009.03.011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

From the aerial parts of Marrubium thessalum, four labdane diterpenes, 13S-preperegrinine, 3 alpha-hydroxymarrubiin, 9 alpha,13R-15,16-bisepoxy-15 beta-methoxy-3-oxo-labdan-6 beta,19-olide and 15-methoxyvelutine C, have been isolated together with four known diterpenes and one methoxylated flavone, ladanein. The structures of the isolated compounds were established by means of NMR (COSY, HSQC, HMBC, NOESY, and ROESY) and MS spectral analyses. Complete NMR assignments are reported for 13R-preperegrinine. Characteristic compounds of the plant were peregrinine and ladanein. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：635 / 640

页数：6

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