Retinal bipolar cells: elementary building blocks of vision

被引:351
作者
Euler, Thomas [1 ,3 ]
Haverkamp, Silke [4 ]
Schubert, Timm [1 ,2 ]
Baden, Tom [1 ,3 ]
机构
[1] Univ Tubingen, Werner Reichardt Ctr Integrat Neurosci CIN, D-72076 Tubingen, Germany
[2] Univ Tubingen, Inst Ophthalm Res, D-72076 Tubingen, Germany
[3] Univ Tubingen, Bernstein Ctr Computat Neurosci Tubingen, D-72076 Tubingen, Germany
[4] Max Planck Inst Brain Res, D-60438 Frankfurt, Germany
关键词
SLOW CONTRAST ADAPTATION; DIRECTION-SELECTIVITY; LIGHT RESPONSE; GANGLION-CELLS; AMACRINE CELLS; DIFFERENTIAL EXPRESSION; PRESYNAPTIC INHIBITION; SYNAPTIC-TRANSMISSION; GLUTAMATE RECEPTORS; WIRING SPECIFICITY;
D O I
10.1038/nrn3783
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Retinal bipolar cells are the first 'projection neurons' of the vertebrate visual system - all of the information needed for vision is relayed by this intraretinal connection. Each of the at least 13 distinct types of bipolar cells systematically transforms the photoreceptor input in a different way, thereby generating specific channels that encode stimulus properties, such as polarity, contrast, temporal profile and chromatic composition. As a result, bipolar cell output signals represent elementary 'building blocks' from which the microcircuits of the inner retina derive a feature-oriented description of the visual world.
引用
收藏
页码:507 / 519
页数:13
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