Effects of oolong tea on plasma antioxidative capacity in mice loaded with restraint stress assessed using the oxygen radical absorbance capacity (ORAC) assay

被引:72
作者
Kurihara, H
Fukami, H
Asami, S
Toyoda, Y
Nakai, M
Shibata, H
Yao, XS
机构
[1] Jinan Univ, Inst Trad Chinese Med & Nat Prod, Guangzhou 510632, Peoples R China
[2] Suntory Ltd, Inst Hlth Care Sci, Osaka 6188503, Japan
关键词
oolong tea; antioxidant; oxygen radical absorbance capacity (ORAC);
D O I
10.1248/bpb.27.1093
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
In the present study, we investigated the antioxidative effect of oolong tea in vitro and in vivo using the oxygen radical absorbance capacity (ORAC) assay. An oolong tea extract, catechin and related compounds suppressed the oxidation of fluorescence induced by AAPH in a dose-dependent manner, that is, they prolonged the antioxidant time in vitro. Oral administration of the oolong tea extract to mice treated with restraint stress increased ORAC activity in plasma as compared with a stress control group. The extract also increased plasma vitamin C levels, and there was a good relationship between ORAC activity and the vitamin C level in plasma. The elevation of plasma ORAC and vitamin C level may have been related to the stress-relieving effect of oolong tea. These effects are probably due to the antioxidative properties of the tea. Thus, these findings suggested that oolong tea has beneficial effects on health related to its antioxidative action.
引用
收藏
页码:1093 / 1098
页数:6
相关论文
共 39 条
[1]   Direct evidence of caeruloplasmin antioxidant properties [J].
Atanasiu, RL ;
Stea, D ;
Mateescu, MA ;
Vergely, C ;
Dalloz, F ;
Briot, F ;
Maupoil, V ;
Nadeau, R ;
Rochette, L .
MOLECULAR AND CELLULAR BIOCHEMISTRY, 1998, 189 (1-2) :127-135
[2]   Determination of tea components with antioxidant activity [J].
Cabrera, C ;
Giménez, R ;
López, MC .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2003, 51 (15) :4427-4435
[3]  
CAO G, 1995, CLIN CHEM, V41, P1738
[4]   Increases in human plasma antioxidant capacity after consumption of controlled diets high in fruit and vegetables [J].
Cao, GH ;
Booth, SL ;
Sadowski, JA ;
Prior, RL .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1998, 68 (05) :1081-1087
[5]   PARTNERS IN DEFENSE, VITAMIN-E AND VITAMIN-C [J].
CHAN, AC .
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1993, 71 (09) :725-731
[6]   Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate [J].
Choi, JY ;
Park, CS ;
Kim, DJ ;
Cho, MH ;
Jin, BK ;
Pie, JE ;
Chung, WG .
NEUROTOXICOLOGY, 2002, 23 (03) :367-374
[7]  
Czlonkowska Anna, 2002, Med Sci Monit, V8, pRA165
[8]  
Edwin D, 2002, J ENVIRON BIOL, V23, P373
[9]  
Esch Tobias, 2003, Med Sci Monit, V9, pRA23
[10]   Exercise, free radical generation, and aging [J].
Fielding, RA ;
Meydani, M .
AGING-CLINICAL AND EXPERIMENTAL RESEARCH, 1997, 9 (1-2) :12-18