Genetic Testing and Corresponding Services Among Individuals With Autism Spectrum Disorder (ASD)

被引:30
作者
Cuccaro, Michael L. [1 ]
Czape, Kayla [1 ]
Alessandri, Michael [2 ]
Lee, Joycelyn [1 ]
Deppen, Abigail Rupchock [1 ]
Bendik, Elise [1 ]
Dueker, Nicole [1 ]
Nations, Laura [3 ]
Pericak-Vance, Margaret [1 ]
Hahn, Susan [1 ]
机构
[1] Univ Miami, Miller Sch Med, Hussman Inst Human Genom, Dr John T McDonald Dept Human Genet, Miami, FL 33136 USA
[2] Univ Miami, Dept Psychol, Coral Gables, FL 33124 USA
[3] Univ N Carolina, Sch Med, Carolina Inst Intellectual Disabil, Chapel Hill, NC USA
关键词
autism spectrum disorder; genetic testing; parental attitudes; survey research; RISK; RECURRENCE;
D O I
10.1002/ajmg.a.36698
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The purpose of this study was to assess use of genetic testing and corresponding genetic services for children with Autism Spectrum Disorder (ASD). Survey data from 397 parents of individuals with ASD was collected using the Center for Autism and Related Disabilities client registry. Participants reported that 41.2% of the individuals with ASD had undergone any type of genetic testing. However, only 21.3% of individuals with ASD had been referred to a genetics specialist. Diagnosis and level of functioning were significantly associated with both referral to a genetics specialist and having undergone any genetic testing. In addition, Hispanic ancestry was associated with increased referral to genetic testing. Concerns about the limited benefits of genetic testing and prohibitive costs were potential barriers to pursuing genetic testing. Overall, low numbers of individuals with ASD have a history of undergoing genetic testing or receiving genetic services. Possible reasons include low referral rates as well as concerns by parents about cost and relevance, and lack of availability. These findings confirm the historical trend for providing genetic testing and genetic services to those with the greatest impairments. (C) 2014 Wiley Periodicals, Inc.
引用
收藏
页码:2592 / 2600
页数:9
相关论文
共 50 条
  • [21] Music Therapy Services for Individuals with Autism Spectrum Disorder: A Survey of Clinical Practices and Training Needs
    Kern, Petra
    Rivera, Nicole R.
    Chandler, Alie
    Humpal, Marcia
    JOURNAL OF MUSIC THERAPY, 2013, 50 (04) : 274 - 303
  • [22] Developing zebrafish models of autism spectrum disorder (ASD)
    Stewart, Adam Michael
    Nguyen, Michael
    Wong, Keith
    Poudel, Manoj K.
    Kalueff, Allan V.
    PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2014, 50 : 27 - 36
  • [23] Autism Spectrum Disorder (ASD): Emotional Intervention Protocol
    Benedicto, Gema
    Val, Mikel
    Fernandez, Eduardo
    Sanchez Ferrer, Francisco
    Manuel Ferrandez, Jose
    ARTIFICIAL INTELLIGENCE IN NEUROSCIENCE: AFFECTIVE ANALYSIS AND HEALTH APPLICATIONS, PT I, 2022, 13258 : 310 - 322
  • [24] In utero immune programming of autism spectrum disorder (ASD)
    Jash, Sukanta
    Sharma, Surendra
    HUMAN IMMUNOLOGY, 2021, 82 (05) : 379 - 384
  • [25] Evaluation of Diagnostic and Therapeutic Services in German University Hospitals for Adults with Autism Spectrum Disorder (ASD)
    Michel, T. M.
    Sheldrick, A. J.
    Frentzel, T. G.
    Herpertz-Dahlmann, B.
    Herpertz, S.
    Habel, U.
    Bruegmann, E.
    Schneider, K.
    Schneider, F.
    FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE, 2010, 78 (07) : 402 - 413
  • [26] Association of schizophrenia spectrum and autism spectrum disorder (ASD) symptoms in children with ASD and clinic controls
    Gadow, Kenneth D.
    RESEARCH IN DEVELOPMENTAL DISABILITIES, 2013, 34 (04) : 1289 - 1299
  • [27] Factors Affecting Family Compliance with Genetic Testing of Children Diagnosed with Autism Spectrum Disorder
    Hendel, Yonah
    Meiri, Gal
    Flusser, Hagit
    Michaelovski, Analya
    Dinstein, Ilan
    Menashe, Idan
    JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 2021, 51 (04) : 1201 - 1209
  • [28] Factors Affecting Family Compliance with Genetic Testing of Children Diagnosed with Autism Spectrum Disorder
    Yonah Hendel
    Gal Meiri
    Hagit Flusser
    Analya Michaelovski
    Ilan Dinstein
    Idan Menashe
    Journal of Autism and Developmental Disorders, 2021, 51 : 1201 - 1209
  • [29] Serum amino acid spectrum in children with autism spectrum disorder (ASD)
    Skalny, Anatoly, V
    Skalny, Andrey A.
    Lobanova, Yulia N.
    Korobeinikova, Tatiana, V
    Ajsuvakova, Olga P.
    Notova, Svetlana, V
    Burtseva, Tatiana, I
    Skalnaya, Margarita G.
    Tinkov, Alexey A.
    RESEARCH IN AUTISM SPECTRUM DISORDERS, 2020, 77
  • [30] Genomic and genetic aspects of autism spectrum disorder
    Liu, Xiaoxi
    Takumi, Toru
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, 452 (02) : 244 - 253