SIMPLE AND EFFICIENT SYNTHESIS OF PHOSPHORYLATED THIENOPYRIDONES FROM 2-AMINOTHIOPHENE-3-CARBOXYLATES AND β-PHOSPHONYLKETONES

被引：3

作者：

Khalladi, Khaoula ^{[1
]}

Touil, Soufiarte ^{[1
]}

机构：

[1] Univ Carthage, Fac Sci Bizerta, Dept Chem, Lab Heteroatorn Organ Chem, Jarzouna 7021, Tunisia

来源：

HETEROCYCLES | 2014年 / 89卷 / 03期

关键词：

LAWESSONS REAGENT; ACIDS; KETOPHOSPHONATES; 2-AMINO-3-CYANOTHIOPHENES; ANTIBACTERIALS; DERIVATIVES; KETO;

D O I：

10.3987/COM-14-12940

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Herein, we report an efficient and straightforward synthesis of the new 5-phosphonothieno[2,3-b]pyridin-4(5H)-ones, via the p-toluenesulfonic acid catalyzed reaction of ethyl 2-aminothiophene-3-carboxylates with beta-phosphonylketones. To the best of our knowledge, this is the first synthesis of thienopyridone derivatives bearing a phosphonate or a phosphine oxide group.

引用

页码：753 / 761

页数：9

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