Close correlation between chronic sclerosing sialadenitis and immunoglobulin G4

被引:27
作者
Kamisawa, T. [1 ]
Nakajima, H.
Hishima, T.
机构
[1] Tokyo Metropolitan Komagome Hosp, Dept Internal Med, Tokyo, Japan
[2] Tokyo Metropolitan Komagome Hosp, Dept Pathol, Tokyo, Japan
关键词
chronic sclerosing sialadenitis; immunoglobulin G4; autoimmune pancreatiti;
D O I
10.1111/j.1445-5994.2006.01119.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In four patients with chronic sclerosing sialadenitis, serum immunoglobulin G4 concentration was markedly increased and abundant infiltration of immunoglobulin G4-positive plasma cells was observed in the salivary glands. Autoimmune pancreatitis occurred in the two patients during follow up. Chronic sclerosing sialadenitis and autoimmune pancreatitis would appear to show essentially the same pathophysiological mechanism. Measurement of serum immunoglobulin G4 concentration is useful in differentiating chronic sclerosing sialadenitis from neoplasia.
引用
收藏
页码:527 / 529
页数:3
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