Comparative In Vitro Susceptibilities of Human Mycoplasmas and Ureaplasmas to a New Investigational Ketolide, CEM-101

被引：75
作者：
Waites, Ken B. [1 ]
Crabb, D. M. [1 ]
Duffy, Lynn B. [1 ]
机构：
[1] Univ Alabama, Dept Pathol, Birmingham, AL 35249 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2009年 / 53卷 / 05期
关键词：
MACROLIDE RESISTANCE; PNEUMONIAE; ANTIMICROBIALS; GENE;
D O I：
10.1128/AAC.00090-09
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
MICs were determined for an investigational ketolide, CEM-101, and azithromycin, telithromycin, doxycycline, levofloxacin, clindamycin, and linezolid against 36 Mycoplasma pneumoniae, 5 Mycoplasma genitalium, 13 Mycoplasma hominis, 15 Mycoplasma fermentans, and 20 Ureaplasma isolates. All isolates, including two macrolide-resistant M. pneumoniae isolates, were inhibited by CEM-101 at <= 0.5 mu g/ml, making CEM-101 the most potent compound tested.
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收藏
页码：2139 / 2141
页数：3
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