A Bayesian network to optimise sample size for food allergen monitoring

被引:13
作者
Elegbede, C. F. [1 ]
Papadopoulos, Alexandra [1 ]
Gauvreau, Julie [1 ]
Crepet, Amelie [1 ]
机构
[1] French Agcy Food Environm & Occupat Hlth Safety A, Risk Assessment Dept DER, Maisons Alfort, France
关键词
Sample size optimisation; Bayesian modelling; Peanut allergens; Labelling; PEANUT ARACHIS-HYPOGAEA; RISK-ASSESSMENT; TOTAL DIET; TRACES; ELISA; PROTEIN; LIST;
D O I
10.1016/j.foodcont.2014.06.039
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Generally, sampling size is optimised considering a single specific constraint. However, for financial reasons, only one sample is usually defined and used to satisfy several objectives. It is therefore crucial to choose a sample that meets all the required objectives. This paper proposes an original method for optimising a sample plan to monitor allergen traces in products consumed by allergy sufferers. The proposed method, based on a Bayesian network, enables several different constraints to be considered within a single model and the integration of literature data on concentration levels of allergen traces in food. Moreover, the construction of a three-stage sampling plan took into account the consumption preferences of peanut allergy sufferers between products with or without labels on the presence of allergen traces, and between the categories and subcategories of products. This method was applied to data from the MIRABEL project which aims to assess risks related to peanut traces for French allergy sufferers. The results show how the model used all the available information and constraints to balance the total number of samples set at 900 for food categories/subcategories and labelling types. As required, the model favoured the most consumed product categories and subcategories. At the same time, it increased the number of samples when peanut concentration is low. This helps reduce the uncertainty on peanut concentrations in these products and consequently on risk estimation. In conclusion, the proposed method is a useful tool for public administrations, risk assessors and risk managers to improve sampling plans for monitoring allergen traces or other health hazards in food. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:212 / 220
页数:9
相关论文
共 34 条
  • [11] Peanut allergy in France: Preliminary results of the pilot study of the project MIRABEL: "Analysis of risk, benefit, cost of peanut allergy"
    Guenard-Bilbault, L.
    Moneret-Vautrin, D. -A.
    Papadopoulos, A.
    Beaumont, P.
    Menetrey, C.
    Beaudouin, E.
    Gayraud, J.
    Drouet, M.
    Sansas, B.
    Crepet, A.
    [J]. REVUE FRANCAISE D ALLERGOLOGIE, 2012, 52 (08): : 509 - 514
  • [12] Consumer attitudes and risks associated with packaged foods having advisory labeling regarding the presence of peanuts
    Hefle, Susan L.
    Furlong, Terence J.
    Niemann, Lynn
    Lemon-Mule, Heather
    Sicherer, Scott
    Taylor, Steve L.
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 120 (01) : 171 - 176
  • [13] Indirect competitive ELISA for determination of traces of peanut (Arachis hypogaea L.) protein in complex food matrices
    Holzhauser, T
    Vieths, S
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1999, 47 (02) : 603 - 611
  • [14] Determination of peanut traces in food by a commercially-available ELISA test
    Keck-Gassenmeier, B
    Bénet, S
    Rosa, C
    Hischenhuber, C
    [J]. FOOD AND AGRICULTURAL IMMUNOLOGY, 1999, 11 (03) : 243 - 250
  • [15] INTRODUCTION TO SAMPLE-SIZE DETERMINATION AND POWER ANALYSIS FOR CLINICAL-TRIALS
    LACHIN, JM
    [J]. CONTROLLED CLINICAL TRIALS, 1981, 2 (02): : 93 - 113
  • [16] Estimated dietary exposure to principal food mycotoxins from The First French Total Diet Study
    Leblanc, JC
    Tard, A
    Volatier, JL
    Verger, P
    [J]. FOOD ADDITIVES AND CONTAMINANTS, 2005, 22 (07): : 652 - 672
  • [17] The BUGS project: Evolution, critique and future directions
    Lunn, David
    Spiegelhalter, David
    Thomas, Andrew
    Best, Nicky
    [J]. STATISTICS IN MEDICINE, 2009, 28 (25) : 3049 - 3067
  • [18] Bayesian Sample Size Determination for Binomial Proportions
    M'Lan, Cyr E.
    Joseph, Lawrence
    Wolfson, David B.
    [J]. BAYESIAN ANALYSIS, 2008, 3 (02): : 269 - 296
  • [19] OQALI: A French database on processed foods
    Menard, C.
    Dumas, C.
    Goglia, R.
    Spiteri, M.
    Gillot, N.
    Combris, P.
    Ireland, J.
    Soler, L. G.
    Volatier, J. L.
    [J]. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 2011, 24 (4-5) : 744 - 749
  • [20] Epidemiology of food allergy
    Moneret-Vautrin, D. -A.
    [J]. REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE, 2008, 48 (03): : 171 - 178