Locomotion, cognition and influences of nutrition in ageing

被引:18
作者
Ayers, Emmeline [1 ]
Verghese, Joe [1 ,2 ]
机构
[1] Albert Einstein Coll Med, Saul R Korey Dept Neurol, Div Cognit & Motor Aging, Bronx, NY 10461 USA
[2] Montefiore Med Ctr, Albert Einstein Coll Med, Dept Med, Bronx, NY 10467 USA
关键词
Ageing; Gait; Nutrition; Cognition; QUALITY-OF-LIFE; WHITE-MATTER LESIONS; VITAMIN-D STATUS; PHYSICAL PERFORMANCE; GAIT DISORDERS; INFLAMMATORY MARKERS; ALZHEIMERS-DISEASE; MEDITERRANEAN DIET; RISK-FACTORS; SYSTEMIC INFLAMMATION;
D O I
10.1017/S0029665113003716
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Gait and cognitive impairments in older adults can reflect the simultaneous existence of two syndromes that affect certain brain substrates and pathologies. Nutritional deficiencies, which are extremely common among elderly population worldwide, have potential to impact the existence and rehabilitation of both syndromes. Gait and cognition are controlled by brain circuits which are vulnerable to multiple age-related pathologies such as vascular diseases, inflammation and dementias that may be caused or accentuated by poor nutrition or deficiencies that lead to cognitive, gait or combined cognitive and gait impairments. The following review aims to link gait and cognitive classifications and provide an overview of the potential impact of nutritional deficiencies on both neurological and gait dysfunctions. The identification of common modifiable risk factors, such as poor nutrition, may serve as an important preventative strategy to reduce cognitive and mobility impairments and moderate the growing burden of dementia and disability worldwide.
引用
收藏
页码:302 / 308
页数:7
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