The MRI-detected osteophyte score is a predictor for undergoing joint replacement in patients with end-stage knee osteoarthritis

被引：12

作者：

Liu, Lizu ^{[1
,2
]}

Ishijima, Muneaki ^{[1
,2
]}

Kaneko, Haruka ^{[1
]}

Sadatsuki, Ryo ^{[1
]}

Hada, Shinnosuke ^{[1
]}

Kinoshita, Mayuko ^{[1
]}

Aoki, Takako ^{[2
]}

Futami, Ippei ^{[1
]}

Yusup, Anwarjan ^{[1
,3
]}

Arita, Hitoshi ^{[1
]}

Shiozawa, Jun ^{[1
]}

Takazawa, Yuji ^{[1
]}

Ikeda, Hiroshi ^{[1
]}

Kaneko, Kazuo ^{[1
,2
]}

机构：

[1] Juntendo Univ, Dept Med Orthopaed & Motor Organ, Grad Sch Med, Tokyo, Japan

[2] Juntendo Univ, Grad Sch Med, Sportol Ctr, Tokyo, Japan

[3] Juntendo Univ, Res Inst Dis Old Age, Grad Sch Med, Tokyo, Japan

来源：

MODERN RHEUMATOLOGY | 2017年 / 27卷 / 02期

关键词：

Activity of daily living; MRI; Osteoarthritis; Osteophyte; Total knee arthroplasty; BONE-MARROW LESIONS; QUANTITATIVE RADIOGRAPHIC FEATURES; ARTICULAR-CARTILAGE; OUTCOME MEASURE; DEFINE STATES; HOME EXERCISE; CHECK COHORT; FOLLOW-UP; HIP; ARTHROPLASTY;

D O I：

10.1080/14397595.2016.1206509

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objectives: The aim of this prospective cohort study was to examine whether MRI-detected osteoarthritis (OA)-structural changes at baseline could predict knee OA patients who would undergo total knee arthroplasty (TKA).Methods: In total, 128 end-stage medial-type knee OA patients were enrolled and followed up for 6 months. MRI using the whole-organ MRI scoring (WORMS) method, radiographic findings, visual analog scale (VAS) for pain and a patient-oriented outcome measure, and the Japanese Knee Osteoarthritis Measure (JKOM) were recorded at baseline. The area under the curve (AUC) was estimated to determine the discriminative value of the prediction models.Results: While 74 patients (57.8%) did not undergo TKA, the remaining 54 patients (42.2%) underwent TKA during this period. The AUCs of the receiver operating characteristic (ROC) curve for the activities of daily living (ADL) score evaluated by the JKOM ADL score [0.70 (95% CI: 0.60-0.79)] and osteophyte score [0.72 (0.64-0.81)] were 0.70 or greater. The JKOM ADL score (17/40) and the osteophyte score (30/98) showed relative risks (RR) of 2.61 (1.32-5.15) and 3.01 (1.39-6.52) for undergoing TKA, respectively.Conclusion: The osteophyte score detected by MRI, in addition to ADL score, was found to be an important factor in determining whether the patient should undergo TKA.

引用

页码：332 / 338

页数：7

共 44 条

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