Adjustment of serum markers in first trimester screening

被引：10

作者：

Lambert-Messerlian, Geralyn ^{[1
,2
]}

Palomaki, Glenn E. ^{[2
]}

Canick, Jacob A. ^{[2
]}

机构：

[1] Brown Univ, Women & Infants Hosp, Dept Pathol & Lab Med, Div Med Screening & Special Testing, Providence, RI 02903 USA

[2] Brown Univ, Alpert Med Sch, Providence, RI 02903 USA

来源：

JOURNAL OF MEDICAL SCREENING | 2009年 / 16卷 / 02期

关键词：

NUCHAL TRANSLUCENCY THICKNESS; DOWNS-SYNDROME; TWIN PREGNANCIES; 1ST-TRIMESTER; ULTRASOUND;

D O I：

10.1258/jms.2009.009028

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

First trimester combined screening can be performed using maternal serum pregnancy-associated plasma protein A, total human chorionic gonadotropin (hCG) and ultrasound measurement of nuchal translucency at 11-13 weeks of pregnancy. Our objective was to explore the effects of covariates on total hCG in the first trimester. First trimester total hCG levels were significantly increased in twins (median = 1.87 MoM), mildly increased in pregnancies achieved by in vitro fertilization (1.04 MoM) and decreased in smokers (0.80 MoM).

引用

页码：102 / 103

页数：2

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