A self-assembling β-peptide hydrogel for neural tissue engineering

被引：75

作者：

Motamed, S. ^{[1
]}

Del Borgo, M. P. ^{[2
,3
]}

Kulkarni, K. ^{[4
]}

Habila, N. ^{[2
,3
]}

Zhou, K. ^{[1
]}

Perlmutter, P. ^{[4
]}

Forsythe, J. S. ^{[1
]}

Aguilar, M. I. ^{[2
,3
]}

机构：

[1] Monash Univ, Monash Inst Med Engn, Dept Mat Sci & Engn, Clayton, Vic 3800, Australia

[2] Monash Univ, Monash Biomed Discovery Inst, Clayton, Vic 3800, Australia

[3] Monash Univ, Dept Biochem & Mol Biol, Clayton, Vic 3800, Australia

[4] Monash Univ, Sch Chem, Clayton, Vic 3800, Australia

来源：

SOFT MATTER | 2016年 / 12卷 / 08期

关键词：

AMINO-ACID; IN-VITRO; PROTEOLYTIC STABILITY; NEURITE OUTGROWTH; SCAFFOLD; BIOMATERIALS; NANOFIBERS; DESIGN; REPAIR; NANO;

D O I：

10.1039/c5sm02902c

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We report a new class of beta-peptide based hydrogel for neural tissue engineering. Our beta-peptide forms a network of nanofibres in aqueous solution, resulting in a stable hydrogel at physiological conditions. The hydrogel shows excellent compatibility with neural cells and provides a suitable environment for cells to adhere and proliferate.

引用

页码：2243 / 2246

页数：4

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