A Critique of the Drug Discovery and Phase 3 Clinical Programs Targeting the Amyloid Hypothesis for Alzheimer Disease

被引:217
作者
Karran, Eric [1 ,2 ,3 ]
Hardy, John [2 ,3 ]
机构
[1] Alzheimers Res UK, Cambridge CB21 6AD, England
[2] Reta Lila Weston Labs, London, England
[3] UCL, Dept Mol Neurosci, London, England
基金
英国惠康基金;
关键词
GAMMA-SECRETASE INHIBITOR; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; TRANSGENIC MOUSE MODEL; BETA IN-VIVO; A-BETA; CEREBROSPINAL-FLUID; COGNITIVE IMPAIRMENT; R-FLURBIPROFEN; PEPTIDE; IMMUNIZATION;
D O I
10.1002/ana.24188
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
[No abstract available]
引用
收藏
页码:185 / 205
页数:21
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