Oncologic Outcome of Intersphincteric Resection for Very Low Rectal Cancer

被引：77

作者：

Saito, Norio ^{[1
]}

Sugito, Masanori ^{[1
]}

Ito, Masaaki ^{[1
]}

Kobayashi, Akihiro ^{[1
]}

Nishizawa, Yusuke ^{[1
]}

Yoneyama, Yasuo ^{[1
]}

Nishizawa, Yuji ^{[1
]}

Minagawa, Nozomi ^{[1
]}

机构：

[1] Natl Canc Ctr Hosp E, Dept Surg Oncol, Colorectal & Pelv Surg Div, Chiba 2778577, Japan

来源：

WORLD JOURNAL OF SURGERY | 2009年 / 33卷 / 08期

关键词：

TOTAL MESORECTAL EXCISION; AUTONOMIC NERVE PRESERVATION; DIRECT COLOANAL ANASTOMOSIS; SPHINCTER-SAVING RESECTION; LOW ANTERIOR RESECTION; LOCAL RECURRENCE; ANAL-SPHINCTER; LOWER; 3RD; CARCINOMA; SURGERY;

D O I：

10.1007/s00268-009-0079-2

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Background In 2000 we launched a prospective program of intersphincteric resection (ISR) for very low rectal cancer. In this study we compared the oncologic outcome of patients who underwent ISR with the outcome of patients who underwent abdominoperineal resection (APR). Methods The data of 202 patients with very low rectal cancer who underwent curative ISR (n = 132) or curative APR (n = 70) between 1995 and 2006 were analyzed. Patients were divided into ISR and APR groups. Survival and local recurrence were investigated in both groups. Results The median follow-up was 40 months in the ISR group and 57 months in the APR group. The 5-year local relapse-free survival rate was 83% in the ISR group and 80% in the APR group (p = 0.364), and the 5-year disease-free survival rate was 69% in the ISR group and 63% in the APR group (p = 0.714). Conclusions For very low rectal cancers, ISR appears to be oncologically acceptable and can reduce the number of APRs.

引用

页码：1750 / 1756

页数：7

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