Point-of-care monitoring for the management of trauma-induced bleeding

被引:17
作者
Hanke, Alexander A. [1 ]
Horstmann, Hauke [2 ]
Wilhelmi, Michaela [3 ]
机构
[1] Hannover Med Sch, Klin Anasthesiol & Intens Med, Hannover, Germany
[2] Diakovere Annastift, Klin Orthopadie, Hannover, Germany
[3] Hannover Med Sch, Klin Unfallchirurg, Hannover, Germany
关键词
aggregometry; point-of-care; ROTEM; TEG; trauma-induced coagulopathy; ROTATIONAL THROMBOELASTOMETRY; PLATELET DYSFUNCTION; INDUCED COAGULOPATHY; MASSIVE TRANSFUSION; CARDIAC-SURGERY; MAJOR TRAUMA; ANTIFIBRINOLYTIC THERAPY; COAGULATION MANAGEMENT; EARLY PREDICTION; SEVERE INJURY;
D O I
10.1097/ACO.0000000000000448
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Purpose of review Knowledge of trauma-induced coagulopathy has been grown in the past and point-of-care suitable devices for coagulation testing have been introduced. Methodology and clinical application of different systems for point-of-care coagulation monitoring are shown with a focus on thrombelastography as measured by TEG, rotational thromboelastometry as measured by ROTEM and impedance aggregometry as measured by the multiplate analyser and ROTEM platelet. Recent findings Two different methods for point-of-care coagulation assessment are available: viscoelastic tests (ROTEM, TEG) and impedance aggregometry. In different settings these methods have been evaluated in various publications pointing out the possibility of reducing transfusion requirements, transfusion-related side effects, and resulting costs. Summary Point-of-care assessment of coagulation in trauma patients appears to be at least promising. However, because published data mostly are of retrospective or observational nature only, there is a need for prospective, randomized and controlled studies.
引用
收藏
页码:250 / 256
页数:7
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