Guidance for the prevention and treatment of cancer-associated venous thromboembolism

被引：149

作者：

Khorana, Alok A. ^{[1
,2
]}

Carrier, Marc ^{[3
]}

Garcia, David A. ^{[4
]}

Lee, Agnes Y. Y. ^{[5
,6
]}

机构：

[1] Cleveland Clin, Taussig Canc Inst, Cleveland, OH 44195 USA

[2] Cleveland Clin, Case Comprehens Canc Ctr, Cleveland, OH 44195 USA

[3] Univ Ottawa, Dept Med, Ottawa Hosp Res Inst, Ottawa, ON, Canada

[4] Univ Washington, Div Hematol, Sch Med, Seattle, WA 98195 USA

[5] Univ British Columbia, Dept Med, Vancouver, BC, Canada

[6] Vancouver Coastal Hlth Author, Vancouver, BC, Canada

来源：

JOURNAL OF THROMBOSIS AND THROMBOLYSIS | 2016年 / 41卷 / 01期

关键词：

Venous thromboembolism; Prevention; Risk factors; Cancer; Direct oral anticoagulants (DOAC); New oral anticoagulants (NOAC); PATIENTS RECEIVING CHEMOTHERAPY; MOLECULAR-WEIGHT HEPARIN; DEEP-VEIN THROMBOSIS; PULMONARY-EMBOLISM; RISK; EVENTS; THROMBOPROPHYLAXIS; COMPLICATIONS; TINZAPARIN; PREDICTION;

D O I：

10.1007/s11239-015-1313-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Venous thromboembolism (VTE) is a highly prevalent complication of malignancy with emerging changes in incidence, diagnosis and treatment paradigms. This manuscript, initiated by the Anticoagulation Forum, provides clinical guidance based on existing guidelines and consensus expert opinion where guidelines are lacking. We address a) the appropriate workup to search for occult malignancy in patients with idiopathic VTE, b) identification of high-risk cancer patients for primary thromboprophylaxis, c) the appropriate immediate and long-term treatment for people with cancer diagnosed with acute thromboembolism, d) the appropriate duration of anticoagulation and e) the appropriate treatment strategy in patients with recurrent VTE on anticoagulation. Areas of controversy and future directions in this field are highlighted.

引用

页码：81 / 91

页数：11

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