Outcome of "Mushroom" Pattern Femtosecond Laser-Assisted Keratoplasty Versus Conventional Penetrating Keratoplasty in Patients With Keratoconus

被引:32
作者
Levinger, Eliya [1 ]
Trivizki, Omer [1 ]
Levinger, Shmuel [2 ]
Kremer, Israel [2 ]
机构
[1] Tel Aviv Univ, Tel Aviv Sourasky Med Ctr, Sackler Fac Med, Dept Ophthalmol, IL-69978 Tel Aviv, Israel
[2] Enaim Med Ctr, IL-9438307 Jerusalem, Israel
关键词
keratoconus; femtosecond; astigmatism; PKP; DEEP LAMELLAR KERATOPLASTY; ENABLED KERATOPLASTY; WOUND CONFIGURATION; LABORATORY MODEL; SURGERY;
D O I
10.1097/ICO.0000000000000080
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: The aim of this study was to compare the outcomes of "mushroom" femtosecond laser-enabled keratoplasty (M-FLEK) with those of conventional penetrating keratoplasty (PKP) in eyes with keratoconus. The femtosecond laser-enabled "mushroom" pattern keratoplasty technique results in less postoperative astigmatism and higher endothelial cell counts compared with conventional PKP in patients with keratoconus. Methods: This was a nonrandomized retrospective, single private center clinical study. Between March 2010 and April 2012, 26 eyes underwent M-FLEK and 33 eyes underwent conventional PKP. Data on preoperative and postoperative manifest refraction, uncorrected visual acuity and best-corrected visual acuity (BCVA), endothelial cell counts, vector analysis, and complications were retrieved and analyzed. Results: At 12 months of follow-up, the mean logMAR BCVA was 0.31 +/- 0.55 in the M-FLEK group and 0.32 +/- 0.21 in the PKP group (P = 0.91). The mean spherical equivalent was similar between the groups. The mean manifest cylinder was significantly lower in the M-FLEK group (-2.84 +/- 1.08 diopters) than in the PKP group (-3.93 +/- 2.26 diopters; P = 0.03). There was a smaller mean endothelial cell loss in the M-FLEK group compared with the PKP group (32.1% vs 38.7%, respectively, P = 0.17) 1 year postoperatively. The complication rates were similar for both groups. Conclusions: M-FLEK appears to be a safe procedure that results in less astigmatism and a trend toward higher endothelial cell counts compared with conventional PKP, with similar postoperative BCVA.
引用
收藏
页码:481 / 485
页数:5
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