Chitosan-based hydrogels: From preparation to biomedical applications

被引：445
作者：
Pella, Michelly C. G. [1 ]
Lima-Tenorio, Michele K. [2 ]
Tenorio-Neto, Ernandes T. [2 ]
Guilherme, Marcos R. [1 ]
Muniz, Edvani C. [1 ,3 ]
Rubira, Adley F. [1 ]
机构：
[1] Univ Estadual Maringa, Dept Chem, Ave Colombo 5790, BR-87020900 Maringa, Parana, Brazil
[2] Univ Estadual Ponta Grossa, Dept Chem, Ave Gen Carlos Cavalcanti 4748, BR-84030900 Ponta Grossa, Parana, Brazil
[3] Fed Univ Technol, Parana UTFPR LD, Postgrad Program Mat Sci & Engn, BR-86036370 Londrina, Parana, Brazil
来源：
CARBOHYDRATE POLYMERS | 2018年 / 196卷
关键词：
Chitosan; Biomaterial; Tissue engineering; Drug delivery; Hydrogel; DRUG-DELIVERY SYSTEM; ACID-BASED HYDROGELS; CROSS-LINKING; CONTROLLED-RELEASE; SUSTAINED-RELEASE; IN-VITRO; COMPOSITE HYDROGEL; HYALURONIC-ACID; CARBOXYMETHYL CHITOSAN; QUATERNIZED CHITOSAN;
D O I：
10.1016/j.carbpol.2018.05.033
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The advances in the field of biomaterials have led to several studies on alternative biocompatible devices and to their development focusing on their properties, benefits, limitations, and utilization of alternative resources. Due to their advantages like biocompatibility, biodegradability, and low cost, polysaccharides have been widely used in the development of hydrogels. Among the polysaccharides studied on hydrogels preparation, chitosan (pure or combined with natural/synthetic polymers) have been widely investigated for use in biomedical field. In view of potential applications of chitosan-based hydrogels, this review focuses on the most recent progress made with respect to preparation, properties, and their salient accomplishments for drug delivery and tissue engineering.
引用
收藏
页码：233 / 245
页数：13
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