Synthesis of new hydrophilic rhodamine based enzymatic substrates compatible with droplet-based microfluidic assays

被引：20

作者：

Fenneteau, Johan ^{[1
]}

Chauvin, Dany ^{[2
]}

Griffiths, Andrew D. ^{[2
]}

Nizak, Clement ^{[2
]}

Cossy, Janine ^{[1
]}

机构：

[1] PSL Res Univ, Lab Chim Organ, Inst Chem Biol & Innovat CBI, UMR 8231,ESPCI Paris,CNRS, 10 Rue Vauquelin, F-75231 Paris 05, France

[2] PSL Res Univ, Lab Biochim, Inst Chem Biol & Innovat CBI, UMR 8231,ESPCI Paris,CNRS, 10 Rue Vauquelin, F-75231 Paris 05, France

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 39期

关键词：

LATENT FLUOROPHORE; DERIVATIVES; EVOLUTION; DYES;

D O I：

10.1039/c7cc01506b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Here we report the conception, synthesis and evaluation of new hydrophilic rhodamine-based enzymatic substrates for detection of peptidase activity compatible with high-throughput screening using droplet-based microfluidics.

引用

页码：5437 / 5440

页数：4