Synthesis of new hydrophilic rhodamine based enzymatic substrates compatible with droplet-based microfluidic assays

被引：20
|
作者：
Fenneteau, Johan [1 ]
Chauvin, Dany [2 ]
Griffiths, Andrew D. [2 ]
Nizak, Clement [2 ]
Cossy, Janine [1 ]
机构：
[1] PSL Res Univ, Lab Chim Organ, Inst Chem Biol & Innovat CBI, UMR 8231,ESPCI Paris,CNRS, 10 Rue Vauquelin, F-75231 Paris 05, France
[2] PSL Res Univ, Lab Biochim, Inst Chem Biol & Innovat CBI, UMR 8231,ESPCI Paris,CNRS, 10 Rue Vauquelin, F-75231 Paris 05, France
来源：
CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 39期
关键词：
LATENT FLUOROPHORE; DERIVATIVES; EVOLUTION; DYES;
D O I：
10.1039/c7cc01506b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Here we report the conception, synthesis and evaluation of new hydrophilic rhodamine-based enzymatic substrates for detection of peptidase activity compatible with high-throughput screening using droplet-based microfluidics.
引用
收藏
页码：5437 / 5440
页数：4
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