MR-Guided Radiotherapy for Rectal Cancer: Current Perspective on Organ Preservation

被引：28

作者：

Boldrini, Luca ^{[1
,2
]}

Intven, Martijn ^{[3
]}

Bassetti, Michael ^{[4
]}

Valentini, Vincenzo ^{[1
,2
]}

Gani, Cihan ^{[5
,6
]}

机构：

[1] Fdn Policlin Univ A Gemelli IRCCS, Unita Operat Complessa Radioterapia Oncol, Dipartimento Diagnost Immagini Radioterapia Oncol, Rome, Italy

[2] Univ Cattolica Sacro Cuore, Ist Radiol, Rome, Italy

[3] Univ Med Ctr Utrecht, Dept Radiat Oncol, Utrecht, Netherlands

[4] Univ Wisconsin, Dept Human Oncol, Madison, WI USA

[5] Eberhard Karls Univ Tubingen, Dept Radiat Oncol, Tubingen, Germany

[6] German Canc Consortium DKTK, Partner Site, Tubingen, Germany

来源：

FRONTIERS IN ONCOLOGY | 2021年 / 11卷

关键词：

radiotherapy; rectal cancer; MRI; MR-linac; dose escalation;

D O I：

10.3389/fonc.2021.619852

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Online MRI-guided radiotherapy (MRgRT) is one of the most recent technological advances in radiotherapy. MRgRT permits the visualization of tumorous and healthy tissue while the patient is on the treatment table and online daily plan adaptations following the observed anatomical changes. In the context of rectal cancer, online MRgRT is a very promising modality due to the pronounced geographical variability of tumor tissues and the surrounding healthy tissues. This current paper will discuss the possible applications of online MRgRT, in particular, in terms of radiotherapy dose escalation and response prediction in organ preservation approaches for rectal cancer.

引用

页数：5

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