A ratiometric electrochemiluminescent cytosensor based on polyaniline hydrogel electrodes in spatially separated electrochemiluminescent systems

被引：5
作者：
Liu, Gen [1 ,2 ,3 ]
Chen, Zixuan [1 ]
Jin, Bao-Kang [3 ]
Jiang, Li-Ping [1 ]
机构：
[1] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Analyt Chem Life Sci, Nanjing 210023, Peoples R China
[2] Huaibei Normal Univ, Coll Chem & Mat Sci, Huaibei 235000, Peoples R China
[3] Anhui Univ, Coll Chem & Chem Engn, Hefei 230601, Peoples R China
来源：
ANALYST | 2021年 / 146卷 / 06期
基金：
中国国家自然科学基金;
关键词：
Polyaniline - Cell membranes;
D O I：
10.1039/d0an02408b
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Here, we proposed a ratiometric electrochemiluminescent (ECL) strategy in spatially multiplied ECL systems. By the specific recognition of hyaluronic acid with proteoglycan CD44 and epidermal growth factor with epidermal growth factor receptor on the cell surface, the cells were labelled with potential-resolved ECL probes, namely Ru(bpy)(3)(2+) and g-C3N4, respectively. The as-proposed cytosensor provides a multichannel ECL protocol to improve the throughput, which may push the application of ECL for the cellular immunoanalysis.
引用
收藏
页码：1835 / 1838
页数：4
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