Dual effects of natural killer cells in transplantation for leukemia

被引：4

作者：

Arima, Nobuyoshi ^{[1
]}

机构：

[1] Shinko Hosp, Dept Hematol, Chuo Ku, 1-4-47 Wakihamacho, Kobe, Hyogo 6510072, Japan

来源：

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2021年 / 158卷

关键词：

Natural killer cells; Killer-cell immunoglobulin-like receptor; HLA class 1; Hematopoietic cell transplantation; Leukemia; Graft versus tumor effect;

D O I：

10.1016/j.critrevonc.2020.103206

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Natural killer (NK) cells were originally considered to belong to the innate immune system to play a protective role against tumor cells and viral infections. In human, they can recognize self and non-self HLA class 1 as their ligand. So, analyzing the outcomes of allogeneic hematopoietic stem cell transplantation is a good opportunity to know the antitumor effects and regulatory effects of NK cells through HLA class 1 matching and mismatching of donor and recipient. In this review, I looked back on the main analysis results of the past transplants, summarized our reports consisting of many cases in a single ethnic, and showed that NK cells might work oppositely depending on the type of leukemia. New treatment strategies based on these concepts may offer individualized treatment options and ultimately increase offer the possibility of a cure for patients with leukemia.

引用

页数：9

共 96 条

[1] Neonatal adaptive immunity comes of age [J].

Adkins, B ;

Leclerc, C ;

Marshall-Clarke, S .

NATURE REVIEWS IMMUNOLOGY, 2004, 4 (07) :553-564

[2] Human NK Cells Differ More in Their KIR2DL1-Dependent Thresholds for HLA-Cw6-Mediated Inhibition than in Their Maximal Killing Capacity [J].

Almeida, Catarina R. ;

Ashkenazi, Amit ;

Shahaf, Gitit ;

Kaplan, Deborah ;

Davis, Daniel M. ;

Mehr, Ramit .

PLOS ONE, 2011, 6 (09)

[3] Human NK cell education by inhibitory receptors for MHC class I [J].

Anfossi, Nicolas ;

Andre, Pascale ;

Guia, Sophie ;

Falk, Christine S. ;

Roetynck, Sophie ;

Stewart, C. Andrew ;

Breso, Violette ;

Frassati, Coralie ;

Reviron, Denis ;

Middleton, Derek ;

Romagne, Francois ;

Ugolini, Sophie ;

Vivier, Eric .

IMMUNITY, 2006, 25 (02) :331-342

[4] Increased Relapse Risk of Acute Lymphoid Leukemia in Homozygous HLA-C1 Patients after HLA-Matched Allogeneic Transplantation: A Japanese National Registry Study [J].

Arima, Nobuyoshi ;

Kanda, Junya ;

Yabe, Toshio ;

Morishima, Yasuo ;

Tanaka, Junji ;

Kako, Shinichi ;

Sakaguchi, Hirotoshi ;

Kato, Motohiro ;

Ohashi, Kazuteru ;

Ozawa, Yukiyasu ;

Fukuda, Takahiro ;

Ota, Shuichi ;

Tachibana, Takayoshi ;

Onizuka, Makoto ;

Ichinohe, Tatsuo ;

Atsuta, Yoshiko ;

Kanda, Yoshinobu .

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2020, 26 (03) :431-437

[5] Homozygous HLA-C1 is Associated with Reduced Risk of Relapse after HLA-Matched Transplantation in Patients with Myeloid Leukemia [J].

Arima, Nobuyoshi ;

Kanda, Junya ;

Tanaka, Junji ;

Yabe, Toshio ;

Morishima, Yasuo ;

Kim, Sung-Won ;

Najima, Yuho ;

Ozawa, Yukiyasu ;

Eto, Tetsuya ;

Kanamori, Heiwa ;

Mori, Takehiko ;

Kobayashi, Naoki ;

Kondo, Tadakazu ;

Nakamae, Hirohisa ;

Uchida, Naoyuki ;

Inoue, Masami ;

Fukuda, Takahiro ;

Ichinohe, Tatsuo ;

Atsuta, Yoshiko ;

Kanda, Yoshinobu .

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2018, 24 (04) :717-725

[6] Influence of Differently Licensed KIR2DL1-Positive Natural Killer Cells in Transplant Recipients with Acute Leukemia: A Japanese National Registry Study [J].

Arima, Nobuyoshi ;

Nakamura, Fumiaki ;

Yabe, Toshio ;

Tanaka, Junji ;

Fuji, Shigeo ;

Ohashi, Kazuteru ;

Fukuda, Takahiro ;

Miyamura, Koichi ;

Iwato, Koji ;

Eto, Tetsuya ;

Mori, Takehiko ;

Kobayashi, Naoki ;

Hoshino, Takumi ;

Kato, Chiaki ;

Kanamori, Heiwa ;

Nakamae, Hirohisa ;

Atsuta, Yoshiko ;

Morishima, Yasuo ;

Kanda, Yoshinobu .

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2016, 22 (03) :423-431

[7] Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor [J].

Balsamo, Mirna ;

Vermi, William ;

Parodi, Monica ;

Pietra, Gabriella ;

Manzini, Claudia ;

Queirolo, Paola ;

Lonardi, Silvia ;

Augugliaro, Raffaella ;

Moretta, Alessandro ;

Facchetti, Fabio ;

Moretta, Lorenzo ;

Mingari, Maria Cristina ;

Vitale, Massimo .

EUROPEAN JOURNAL OF IMMUNOLOGY, 2012, 42 (07) :1833-1842

[8] Expression of KIR2DS1 does not significantly contribute to NK cell cytotoxicity in HLA-C1/C2 heterozygous haplotype B donors [J].

Baltner, Karla ;

Kuebler, Ayline ;

Pal, Marina ;

Balvociute, Monika ;

Mezger, Markus ;

Handgretinger, Rupert ;

Andre, Maya C. .

INTERNATIONAL IMMUNOLOGY, 2017, 29 (09) :423-429

[9] Effect of Donor KIR2DL1 Allelic Polymorphism on the Outcome of Pediatric Allogeneic Hematopoietic Stem-Cell Transplantation [J].

Bari, Rafijul ;

Rujkijyanont, Piya ;

Sullivan, Erin ;

Kang, Guolian ;

Turner, Victoria ;

Gan, Kwan ;

Leung, Wing .

JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (30) :3782-+

[10] Inducible down-regulation of MHC class I results in natural killer cell tolerance [J].

Bern, Michael D. ;

Parikh, Bijal A. ;

Yang, Liping ;

Beckman, Diana L. ;

Poursine-Laurent, Jennifer ;

Yokoyama, Wayne M. .

JOURNAL OF EXPERIMENTAL MEDICINE, 2019, 216 (01) :99-116

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