Synthesis and characterization of biodegradable poly(ε-caprolactone)-polyglycolide-poly(ethylene glycol) monomethyl ether random copolymer

被引：13

作者：

Zhou, SB ^{[1
]}

Xu, JG ^{[1
]}

Yang, H ^{[1
]}

Deng, XM ^{[1
]}

机构：

[1] Chinese Acad Sci, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China

来源：

MACROMOLECULAR MATERIALS AND ENGINEERING | 2004年 / 289卷 / 06期

关键词：

biodegradable; poly(epsilon-caprolactone); random copolymer; ring-opening polymerization;

D O I：

10.1002/mame.200300283

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Poly(epsilon-caprolactone)-polyglycolide-poly(ethlene glycol) monomethyl ether random copolymers were synthesized from epsilon-caprolactone (epsilon-CL), glycolide (GA) and poly(ethylene glycol) monomethyl ether (MPEG) using stannous actotate as catylst at 160degreesC by bulk polymerization. The copolymers with different composition were synthesized by adjusting the weight ration of reaction mixture. The resultant copolymer with a weight ratio (10:15:75) of MPEG2000, GA, and CL was characterized by IR, H-1 NMR, GPC and DSC. The new biodegradable copolymer has potential for medical applications since it if combined with properties of PCI, PGA and MPEG.

引用

页码：576 / 580

页数：5

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