Utility of lung clearance index in CF: What we know, what we don't know and musings on how to bridge the gap

被引：0

作者：

Saiman, Lisa ^{[1
,2
]}

Waters, Valerie ^{[3
,4
,5
]}

Jones, Andrew ^{[6
]}

Drevinek, Pavel ^{[7
,8
,9
]}

机构：

[1] Columbia Univ, Med Ctr, Pediat, New York, NY 10027 USA

[2] New York Presbyterian NYP Morgan Stanley Children, New York, NY 10032 USA

[3] Univ Toronto, Paediat, Toronto, ON, Canada

[4] Hosp Sick Children SickKids, Div Infect Dis, Toronto, ON, Canada

[5] SickKids Res Inst, Translat Med, Toronto, ON, Canada

[6] Manchester Adult Cyst Fibrosis Ctr, Manchester, Lancs, England

[7] Motol Univ Hosp, Med Microbiol, Prague, Czech Republic

[8] Motol Univ Hosp, Dept Med Microbiol, Prague, Czech Republic

[9] Motol Univ Hosp, Cyst Fibrosis Ctr, Prague, Czech Republic

来源：

JOURNAL OF CYSTIC FIBROSIS | 2020年 / 19卷 / 06期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/j.jcf.2020.09.006

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

引用

页码：856 / 857

页数：2

共 41 条

[1] The effect of dornase alfa on ventilation inhomogeneity in patients with cystic fibrosis [J].

Amin, R. ;

Subbarao, P. ;

Lou, W. ;

Jabar, A. ;

Balkovec, S. ;

Jensen, R. ;

Kerrigan, S. ;

Gustafsson, P. ;

Ratjen, F. .

EUROPEAN RESPIRATORY JOURNAL, 2011, 37 (04) :806-812

[2] Hypertonic saline improves the LCI in paediatric patients with CF with normal lung function [J].

Amin, Reshma ;

Subbarao, Padmaja ;

Jabar, Alisha ;

Balkovec, Susan ;

Jensen, Renee ;

Kerrigan, Shawn ;

Gustafsson, Per ;

Ratjen, Felix .

THORAX, 2010, 65 (05) :379-383

[3] Gas mixing efficiency from birth to adulthood measured by multiple-breath washout [J].

Aurora, P ;

Kozlowska, W ;

Stocks, J .

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 2005, 148 (1-2) :125-139

[4] Simultaneous sulfur hexafluoride and nitrogen multiple-breath washout (MBW) to examine inherent differences in MBW outcomes [J].

Bayfield, Katie J. ;

Horsley, Alex ;

Alton, Eric ;

Irving, Samantha ;

Bush, Andrew ;

Davies, Jane C. .

ERJ OPEN RESEARCH, 2019, 5 (04)

[5] Early Cystic Fibrosis Lung Disease Detected by Bronchoalveolar Lavage and Lung Clearance Index [J].

Belessis, Yvonne ;

Dixon, Barbara ;

Hawkins, Glenn ;

Pereira, John ;

Peat, Jenny ;

MacDonald, Rebecca ;

Field, Penny ;

Numa, Andrew ;

Morton, John ;

Lui, Kei ;

Jaffe, Adam .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2012, 185 (08) :862-873

[6] Management of severe asthma in children [J].

Bush, Andrew ;

Saglani, Sejal .

LANCET, 2010, 376 (9743) :814-825

[7] Minimal change in structural, functional and inflammatory markers of lung disease in newborn screened infants with cystic fibrosis at one year [J].

Davies, Gwyneth ;

Thia, Lena P. ;

Stocks, Janet ;

Bush, Andrew ;

Hoo, Ah-Fong ;

Wade, Angie ;

The Thanh Diem Nguyen ;

Brody, Alan S. ;

Calder, Alistair ;

Klein, Nigel J. ;

Carr, Siobhan B. ;

Wallis, Colin ;

Suri, Ranjan ;

Pao, Caroline S. ;

Ruiz, Gary ;

Balfour-Lynn, Ian M. .

JOURNAL OF CYSTIC FIBROSIS, 2020, 19 (06) :896-901

[8] The use of multiple breath washout for assessing cystic fibrosis in infants [J].

Davies, Gwyneth ;

Aurora, Paul .

EXPERT REVIEW OF RESPIRATORY MEDICINE, 2017, 11 (01) :21-28

[9] Assessment of clinical response to ivacaftor with lung clearance index in cystic fibrosis patients with a G551D-CFTR mutation and preserved spirometry: a randomised controlled trial [J].

Davies, Jane ;

Sheridan, Helen ;

Bell, Nicholas ;

Cunningham, Steve ;

Davis, Stephanie D. ;

Elborn, J. Stuart ;

Milla, Carlos E. ;

Starner, Timothy D. ;

Weiner, Daniel J. ;

Lee, Po-Shun ;

Ratjen, Felix .

LANCET RESPIRATORY MEDICINE, 2013, 1 (08) :630-638

[10]

Davies JC, 2020, J CYST FIBROS

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