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- [21] Immune-mediated inflammatory diseases and the risk of valvular heart disease: a Mendelian randomization studyClinical Rheumatology, 2024, 43 : 533 - 541Dihui Cai论文数: 0 引用数: 0 h-index: 0机构: Lihuili Hospital Affiliated to Ningbo University,Department of Cardiology, Ningbo Institute of Innovation for Combined Medicine and EngineeringZequn Zheng论文数: 0 引用数: 0 h-index: 0机构: Lihuili Hospital Affiliated to Ningbo University,Department of Cardiology, Ningbo Institute of Innovation for Combined Medicine and EngineeringJiale Hu论文数: 0 引用数: 0 h-index: 0机构: Lihuili Hospital Affiliated to Ningbo University,Department of Cardiology, Ningbo Institute of Innovation for Combined Medicine and EngineeringYin Fu论文数: 0 引用数: 0 h-index: 0机构: Lihuili Hospital Affiliated to Ningbo University,Department of Cardiology, Ningbo Institute of Innovation for Combined Medicine and EngineeringYongfei Song论文数: 0 引用数: 0 h-index: 0机构: Lihuili Hospital Affiliated to Ningbo University,Department of Cardiology, Ningbo Institute of Innovation for Combined Medicine and EngineeringJiangfang Lian论文数: 0 引用数: 0 h-index: 0机构: Lihuili Hospital Affiliated to Ningbo University,Department of Cardiology, Ningbo Institute of Innovation for Combined Medicine and Engineering
- [22] Plasma levels of the anti-coagulation protein C and the risk of ischaemic heart disease A Mendelian randomisation studyTHROMBOSIS AND HAEMOSTASIS, 2017, 117 (02) : 262 - 268Schooling, C. Mary论文数: 0 引用数: 0 h-index: 0机构: CUNY, Grad Sch Publ Hlth & Hlth Policy, New York, NY 10021 USA Univ Hong Kong, Li Ka Shing Fac Med, Sch Publ Hlth, Hong Kong, Hong Kong, Peoples R China CUNY, Grad Sch Publ Hlth & Hlth Policy, New York, NY 10021 USAZhong, Yi论文数: 0 引用数: 0 h-index: 0机构: Univ Hong Kong, Li Ka Shing Fac Med, Sch Publ Hlth, Hong Kong, Hong Kong, Peoples R China CUNY, Grad Sch Publ Hlth & Hlth Policy, New York, NY 10021 USA
- [23] Relationship between alcohol use, blood pressure and hypertension: an association study and a Mendelian randomisation studyJOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 2019, 73 (09) : 796 - 801Zhao, Pian-Pian论文数: 0 引用数: 0 h-index: 0机构: Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R China Westlake Inst Adv Study, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaXu, Liang-Wen论文数: 0 引用数: 0 h-index: 0机构: Hangzhou Normal Univ, Sch Med, Div Prevent Med, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaSun, Tao论文数: 0 引用数: 0 h-index: 0机构: Suzhou New Century Int Childrens Hosp, Dept Pediat, Suzhou, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaWu, Yin-Yin论文数: 0 引用数: 0 h-index: 0机构: Hangzhou Normal Univ, Sch Med, Div Prevent Med, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaZhu, Xiao-Wei论文数: 0 引用数: 0 h-index: 0机构: Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R China Westlake Inst Adv Study, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaZhang, Bo论文数: 0 引用数: 0 h-index: 0机构: Second Affiliated Hosp Soochow Univ, Dept Radiol, Suzhou, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaCheng, Zhi论文数: 0 引用数: 0 h-index: 0机构: Suzhou Sci & Technol Town Hosp, Dept Pediat, Suzhou, Peoples R China Nanjing Med Univ, Suzhou Hosp, Suzhou, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaCai, Xiao论文数: 0 引用数: 0 h-index: 0机构: Hangzhou Normal Univ, Sch Med, Div Prevent Med, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaLiu, Yu-Chao论文数: 0 引用数: 0 h-index: 0机构: Hangzhou Normal Univ, Sch Med, Div Prevent Med, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaZhao, Ting-Ting论文数: 0 引用数: 0 h-index: 0机构: Hangzhou Normal Univ, Sch Med, Div Prevent Med, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaWu, Ting-Ting论文数: 0 引用数: 0 h-index: 0机构: Hangzhou Normal Univ, Sch Med, Div Prevent Med, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaMa, Hai-Yan论文数: 0 引用数: 0 h-index: 0机构: Hangzhou Normal Univ, Sch Med, Div Prevent Med, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaWang, Li论文数: 0 引用数: 0 h-index: 0机构: Hangzhou Normal Univ, Sch Med, Div Prevent Med, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaZhang, Xing-Wei论文数: 0 引用数: 0 h-index: 0机构: Affiliated Hosp Hangzhou Normal Univ, Dept Cardiol, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaYang, Lei论文数: 0 引用数: 0 h-index: 0机构: Hangzhou Normal Univ, Sch Med, Div Prevent Med, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R ChinaZheng, Hou-Feng论文数: 0 引用数: 0 h-index: 0机构: Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R China Westlake Inst Adv Study, Hangzhou, Zhejiang, Peoples R China Westlake Univ, Dis & Populat DaP Geninfo Lab, Sch Life Sci, Hangzhou, Zhejiang, Peoples R China
- [24] Proton pump inhibitors and the risk of inflammatory bowel disease: a Mendelian randomisation studyGUT, 2024, 73 (12)An, Hongjin论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Dept Gastroenterol & Hepatol, Chengdu, Peoples R China Sichuan Univ, West China Hosp, Dept Gastroenterol & Hepatol, Chengdu, Peoples R ChinaZhong, Min论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Dept Gastroenterol & Hepatol, Chengdu, Peoples R China Sichuan Univ, West China Hosp, Dept Gastroenterol & Hepatol, Chengdu, Peoples R ChinaGan, Huatian论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Dept Geriatr, Chengdu, Peoples R China Sichuan Univ, West China Hosp, Natl Clin Res Ctr Geriatr, Chengdu, Peoples R China Sichuan Univ, West China Hosp, Dept Gastroenterol, Chengdu, Peoples R China Sichuan Univ, West China Hosp, Frontiers Sci Ctr Dis Related Mol Network,Lab Inf, Inst Inflammat & Immunol,Ctr Inflammatory Bowel D, Chengdu, Peoples R China Sichuan Univ, West China Hosp, Dept Gastroenterol & Hepatol, Chengdu, Peoples R China
- [25] Systemic lupus erythematosus is associated with the risk of coeliac disease: a Mendelian randomisation studyAUTOIMMUNITY, 2023, 56 (01)Wang, Qiaolin论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Med Sci & Peking Union Med Coll, Inst Dermatol, Nanjing, Peoples R China Chinese Acad Med Sci, Key Lab Basic & Translat Res Immune Mediated Skin, Nanjing, Peoples R China Chinese Acad Med Sci & Peking Union Med Coll, Inst Dermatol, Nanjing, Peoples R ChinaJia, Sujie论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Med Sci & Peking Union Med Coll, Dept Pharm, Nanjing, Peoples R China Chinese Acad Med Sci & Peking Union Med Coll, Inst Dermatol, Nanjing, Peoples R ChinaLu, Qianjin论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Med Sci & Peking Union Med Coll, Inst Dermatol, Nanjing, Peoples R China Chinese Acad Med Sci, Key Lab Basic & Translat Res Immune Mediated Skin, Nanjing, Peoples R China Chinese Acad Med Sci & Peking union Med Coll, Inst Dermatol, Nanjing 210042, Peoples R China Chinese Acad Med Sci & Peking Union Med Coll, Inst Dermatol, Nanjing, Peoples R ChinaZhao, Ming论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Med Sci & Peking Union Med Coll, Inst Dermatol, Nanjing, Peoples R China Chinese Acad Med Sci, Key Lab Basic & Translat Res Immune Mediated Skin, Nanjing, Peoples R China Chinese Acad Med Sci & Peking union Med Coll, Inst Dermatol, Nanjing 210042, Peoples R China Chinese Acad Med Sci & Peking Union Med Coll, Inst Dermatol, Nanjing, Peoples R China
- [26] Serum magnesium levels and risk of coronary artery disease: Mendelian randomisation studyBMC MEDICINE, 2018, 16Larsson, Susanna C.论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, Inst Environm Med, Unit Nutr Epidemiol, S-17177 Stockholm, Sweden Karolinska Inst, Inst Environm Med, Unit Nutr Epidemiol, S-17177 Stockholm, Sweden论文数: 引用数: h-index:机构:Michaelsson, Karl论文数: 0 引用数: 0 h-index: 0机构: Uppsala Univ, Dept Surg Sci, Uppsala, Sweden Karolinska Inst, Inst Environm Med, Unit Nutr Epidemiol, S-17177 Stockholm, Sweden
- [27] Obesity and risk for liver disease: a two-sample Mendelian randomisation studyBRITISH JOURNAL OF NUTRITION, 2024, 132 (10) : 1403 - 1410An, Wen论文数: 0 引用数: 0 h-index: 0机构: Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R ChinaLuo, Jing论文数: 0 引用数: 0 h-index: 0机构: Peking Univ, Dept Gastroenterol, Ditan Teaching Hosp, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R ChinaYu, Zhe论文数: 0 引用数: 0 h-index: 0机构: Peking Univ, Dept Gastroenterol, Ditan Teaching Hosp, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R ChinaLi, Mengqi论文数: 0 引用数: 0 h-index: 0机构: Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R ChinaWei, Herui论文数: 0 引用数: 0 h-index: 0机构: Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R ChinaSong, Aqian论文数: 0 引用数: 0 h-index: 0机构: Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R ChinaMao, Yuanpeng论文数: 0 引用数: 0 h-index: 0机构: Peking Univ, Dept Gastroenterol, Ditan Teaching Hosp, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R ChinaBian, Hao论文数: 0 引用数: 0 h-index: 0机构: Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R ChinaHe, Lingling论文数: 0 引用数: 0 h-index: 0机构: Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R ChinaXiao, Fan论文数: 0 引用数: 0 h-index: 0机构: Capital Med Univ, Beijing Ditan Hosp, Natl Key Lab Intelligent Tracking & Forecasting In, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Inst Infect Dis, Beijing Key Lab Emerging Infect Dis, Beijing 100015, Peoples R China Beijing Inst Infect Dis, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Natl Ctr Infect Dis, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R ChinaWei, Hongshan论文数: 0 引用数: 0 h-index: 0机构: Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R China Peking Univ, Dept Gastroenterol, Ditan Teaching Hosp, Beijing 100015, Peoples R China Capital Med Univ, Beijing Ditan Hosp, Dept Gastroenterol, Beijing 100015, Peoples R China
- [28] Serum magnesium levels and risk of coronary artery disease: Mendelian randomisation studyBMC Medicine, 16Susanna C. Larsson论文数: 0 引用数: 0 h-index: 0机构: Karolinska Institutet,Unit of Nutritional Epidemiology, Institute of Environmental MedicineStephen Burgess论文数: 0 引用数: 0 h-index: 0机构: Karolinska Institutet,Unit of Nutritional Epidemiology, Institute of Environmental MedicineKarl Michaëlsson论文数: 0 引用数: 0 h-index: 0机构: Karolinska Institutet,Unit of Nutritional Epidemiology, Institute of Environmental Medicine
- [29] Pregnancy associated hypertensive disorders and risk of cardiovascular disease: a mendelian randomisation studyEUROPEAN HEART JOURNAL, 2023, 44论文数: 引用数: h-index:机构:Van der Schouw, Y. T.论文数: 0 引用数: 0 h-index: 0机构: Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands Med Univ Innsbruck, Innsbruck, AustriaOnland-Moret, N. C.论文数: 0 引用数: 0 h-index: 0机构: Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands Med Univ Innsbruck, Innsbruck, AustriaBloemenkamp, K. W. M.论文数: 0 引用数: 0 h-index: 0机构: Wilhelmina Childrens Hosp, Div Women & Baby, Dept Obstet, Utrecht, Netherlands Med Univ Innsbruck, Innsbruck, AustriaSeekircher, L.论文数: 0 引用数: 0 h-index: 0机构: Med Univ Innsbruck, Innsbruck, Austria Med Univ Innsbruck, Innsbruck, Austria论文数: 引用数: h-index:机构:Willeit, P.论文数: 0 引用数: 0 h-index: 0机构: Med Univ Innsbruck, Innsbruck, Austria Med Univ Innsbruck, Innsbruck, AustriaPeters, S. A. E.论文数: 0 引用数: 0 h-index: 0机构: Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands Med Univ Innsbruck, Innsbruck, Austria
- [30] Circulating white blood cell traits and colorectal cancer risk: A Mendelian randomisation studyINTERNATIONAL JOURNAL OF CANCER, 2024, 154 (01) : 94 - 103Constantinescu, Andrei-Emil论文数: 0 引用数: 0 h-index: 0机构: Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, England Univ Bristol, Bristol Med Sch, Populat Hlth Sci, Bristol, England Univ Bristol, Sch Translat Hlth Sci, Bristol Med Sch, Bristol, England Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandBull, Caroline J.论文数: 0 引用数: 0 h-index: 0机构: Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, England Univ Bristol, Bristol Med Sch, Populat Hlth Sci, Bristol, England Univ Bristol, Sch Translat Hlth Sci, Bristol Med Sch, Bristol, England Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandJones, Nicholas论文数: 0 引用数: 0 h-index: 0机构: Swansea Univ, Inst Life Sci, Med Sch, Swansea, Wales Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, England论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:Dimou, Niki论文数: 0 引用数: 0 h-index: 0机构: WHO, Nutr & Metab Branch, Int Agcy Res Canc, Lyon, France Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandBezieau, Stephane论文数: 0 引用数: 0 h-index: 0机构: Ctr Hosp Univ CHU Nantes, Serv Genet Med, Nantes, France Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandBrenner, Hermann论文数: 0 引用数: 0 h-index: 0机构: German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg, Germany German Canc Res Ctr, Div Prevent Oncol, Heidelberg, Germany Natl Ctr Tumor Dis NCT, Heidelberg, Germany German Canc Res Ctr, German Canc Consortium DKTK, Heidelberg, Germany Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandBuchanan, Daniel D.论文数: 0 引用数: 0 h-index: 0机构: Univ Melbourne, Dept Clin Pathol, Colorectal Oncogen Grp, Parkville, Vic, Australia Univ Melbourne, Victorian Comprehens Canc Ctr, Ctr Canc Res, Parkville, Vic, Australia Royal Melbourne Hosp, Genet Med & Family Canc Clin, Parkville, Vic, Australia Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandD'Amato, Mauro论文数: 0 引用数: 0 h-index: 0机构: LUM Univ, Dept Med & Surg, Casamassima, Italy BRTA, Gastrointestinal Genet Lab, CIC bioGUNE, Derio, Spain Basque Fdn Sci, Ikerbasque, Bilbao, Spain Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandJenkins, Mark A.论文数: 0 引用数: 0 h-index: 0机构: Univ Melbourne, Ctr Epidemiol & Biostat, Melbourne Sch Populat & Global Hlth, Melbourne, Vic, Australia Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandMoreno, Victor论文数: 0 引用数: 0 h-index: 0机构: IDIBELL, Catalan Inst Oncol, Oncol Data Analyt Program, Lhospitalet De Llobregat, Barcelona, Spain CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain Univ Barcelona, Fac Med, Dept Clin Sci, Barcelona, Spain Bellvitge Biomed Res Inst IDIBELL, ONCOBEL Program, Lhospitalet De Llobregat, Barcelona, Spain Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandPai, Rish K.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin Arizona, Dept Lab Med & Pathol, Scottsdale, AZ USA Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandUm, Caroline Y.论文数: 0 引用数: 0 h-index: 0机构: Amer Canc Soc, Dept Populat Sci, Atlanta, GA USA Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandWhite, Emily论文数: 0 引用数: 0 h-index: 0机构: Univ Washington, Sch Publ Hlth, Dept Epidemiol, Seattle, WA USA Fred Hutchinson Canc Ctr, Publ Hlth Sci Div, Seattle, WA USA Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandMurphy, Neil论文数: 0 引用数: 0 h-index: 0机构: Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandGunter, Marc论文数: 0 引用数: 0 h-index: 0机构: WHO, Nutr & Metab Branch, Int Agcy Res Canc, Lyon, France Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandTimpson, Nicholas J.论文数: 0 引用数: 0 h-index: 0机构: Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, England Univ Bristol, Bristol Med Sch, Populat Hlth Sci, Bristol, England Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandHuyghe, Jeroen R.论文数: 0 引用数: 0 h-index: 0机构: Fred Hutchinson Canc Ctr, Publ Hlth Sci Div, Seattle, WA USA Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, EnglandVincent, Emma E.论文数: 0 引用数: 0 h-index: 0机构: Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, England Univ Bristol, Bristol Med Sch, Populat Hlth Sci, Bristol, England Univ Bristol, Sch Translat Hlth Sci, Bristol Med Sch, Bristol, England Univ Bristol, MRC Integrat Epidemiol Unit, Bristol, England