Frequency and severity of COVID-19 in multiple sclerosis: A short single-site report from northern Italy

被引:24
作者
Crescenzo, Francesco [1 ]
Marastoni, Damiano [1 ]
Bovo, Chiara [2 ]
Calabrese, Massimiliano [1 ]
机构
[1] Univ Hosp Verona, Neurol Sect, Dept Neurosci Biomed & Movement Sci, Verona, Italy
[2] Univ Hosp Verona, Med Direct, Verona, Italy
关键词
COVID-19; coronavirus; multiple sclerosis;
D O I
10.1016/j.msard.2020.102372
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Neurologists are interested in understanding whether patients with multiple sclerosis (pwMS) undergoing immunomodulatory/immunosuppressive therapy are more susceptible to developing COVID-19 or have worse outcomes. Currently, there are no conclusive data in this regard. We report the prevalence and severity of COVID-19 (confirmed and possible) in pwMS followed at the Veneto Regional MS Center in Verona (Italy), an area most stricken by COVID-19. In our sample size, the prevalence of COVID-19 seems to be much higher than that officially reported at the regional level on the general population, but it also characterized by a favourable course.
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页数:3
相关论文
共 8 条
[1]   COVID-19 and MS disease-modifying therapies [J].
Berger, Joseph R. ;
Brandstadter, Rachel ;
Bar-Or, Amit .
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION, 2020, 7 (04)
[2]   Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study [J].
Chen, Nanshan ;
Zhou, Min ;
Dong, Xuan ;
Qu, Jieming ;
Gong, Fengyun ;
Han, Yang ;
Qiu, Yang ;
Wang, Jingli ;
Liu, Ying ;
Wei, Yuan ;
Xia, Jia'an ;
Yu, Ting ;
Zhang, Xinxin ;
Zhang, Li .
LANCET, 2020, 395 (10223) :507-513
[3]  
Flaxman S, 2020, ESTIMATING NUMBER IN, DOI [10.25561/77731, DOI 10.25561/77731]
[4]   The COVID-19 pandemic and the use of MS disease-modifying therapies [J].
Giovannoni, Gavin ;
Hawkes, Chris ;
Lechner-Scott, Jeannette ;
Levy, Michael ;
Waubant, Emmanuelle ;
Gold, Julian .
MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2020, 39
[5]   Anti-CD20 and COVID-19 in multiple sclerosis and related disorders: A case series of 60 patients from Madrid, Spain [J].
Montero-Escribano, Paloma ;
Matias-Guiu, Jorge ;
Gomez-Iglesias, Patricia ;
Porta-Etessam, Jesus ;
Pytel, Vanesa ;
Matias-Guiu, Jordi A. .
MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2020, 42
[6]   COVID-19 in a MS patient treated with ocrelizumab: does immunosuppression have a protective role? [J].
Novi, Giovanni ;
Mikulska, Malgorzata ;
Briano, Federica ;
Toscanini, Federica ;
Tazza, Francesco ;
Uccelli, Antonio ;
Inglese, Matilde .
MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2020, 42
[7]   Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy [J].
Onder, Graziano ;
Rezza, Giovanni ;
Brusaferro, Silvio .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (18) :1775-1776
[8]   An Italian programme for COVID-19 infection in multiple sclerosis [J].
Sormani, Maria Pia .
LANCET NEUROLOGY, 2020, 19 (06) :481-482