Drastic differences in Crh and HPr synthesis levels reflect their different impacts on catabolite repression in Bacillus subtilis

被引:23
|
作者
Görke, B [1 ]
Fraysse, L [1 ]
Galinier, A [1 ]
机构
[1] Inst Biol Struct & Microbiol, CNRS, UPR 9043, Chim Bacterienne Lab, F-13009 Marseille, France
关键词
D O I
10.1128/JB.186.10.2992-2995.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In Bacillus subtilis, carbon catabolite repression (CCR) of catabolic genes is mediated by ATP-dependent phosphorylation of HPr and Crh. Here we show that the different efficiencies with which these two proteins contribute to CCR may be due to the drastic differences in their synthesis rates under conditions that cause CCR.
引用
收藏
页码:2992 / 2995
页数:4
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  • [1] Evidence for a dimerisation state of the Bacillus subtilis catabolite repression HPr-like protein, Crh
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    Jaquinod, M
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  • [9] CATABOLITE REPRESSION AND NUCLEOTIDES ON AMYLASE SYNTHESIS IN BACILLUS-SUBTILIS
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  • [10] THE HPR PROTEIN OF THE PHOSPHOTRANSFERASE SYSTEM LINKS INDUCTION AND CATABOLITE REPRESSION OF THE BACILLUS-SUBTILIS LEVANASE OPERON
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    RAPOPORT, G
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